Background Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic
liver diseases and has become a huge public health issue worldwide. Inhibition of …

The activation of NOD-like receptor family pyrin domain containing 3 (NLRP3)
inflammasome is closely associated with the development and progression of non-alcoholic …

Background Abnormal activation of NLRP3 inflammasome is related to a series of
inflammatory diseases, including type 2 diabetes, gouty arthritis, non-alcoholic …

Non-alcoholic fatty liver disease (NAFLD) causes liver dysfunction and is associated with
obesity and type 2 diabetes. Chronic inflammation is associated not only with the …

The NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome pathway is
mainly responsible for the activation and release of a cascade of proinflammatory mediators …

The NOD-, LRR-and pyrin domain-containing protein 3 (NLRP3) inflammasome plays a vital
role in mediating the innate immune system. Its aberrant activation contributes to the …

Silybin is one of the effective, traditional Chinese medicines used as a hepatoprotective
agent in nonalcoholic fatty liver disease (NAFLD) therapy worldwide, and the NOD‐like …

Aims Non-alcoholic fatty liver disease (NAFLD) has become one of the most common
chronic liver diseases. The NOD-like receptor protein 3 (NLRP3) inflammasome was …

Alcoholic liver disease (ALD) is a major cause of liver disease worldwide. In patients with
ALD, an increased level of hepatic inflammasome components was observed, together with …

Objectives Despite the recent attention focused on the roles of the NLRP3 inflammasome in
the pathogenesis of metabolic and inflammatory diseases, little is known about the activation …