Mechanical ventilation applies physical stresses to the tissues of the lung and thus may give
rise to ventilator-induced lung injury (VILI), particular in patients with acute respiratory …

This review describes the current understanding of the lungs9 response to deforming stress
under conditions of both normal physiology and acute lung injury. Several limiting …

It may be hard to argue against the thesis that mechanical ventilation represents one of the
most important treatments ever introduced in the care of patients with respiratory failure …

Although mechanical ventilation (MV) is a life-saving intervention for patients with acute
respiratory distress syndrome (ARDS), it can aggravate or cause lung injury, known as …

Since its introduction into the management of the acute respiratory distress syndrome,
mechanical ventilation has been so strongly interwoven with its side effects that it came to be …

The main supportive therapy in acute respiratory distress syndrome patients is mechanical
ventilation. As with any therapy, mechanical ventilation has side-effects, and may induce …

The last two decades have brought new insights into mechanisms of lung injury. These
insights have profoundly altered the ventilator management of patients with adult respiratory …

As with most medical and pharmacologic interventions, mechanical ventilation must be
titrated within a therapeutic window, providing the required lifesustaining support while …

Ventilation-induced lung injury results from mechanical stress and strain that occur during
tidal ventilation in the susceptible lung. Classical descriptions of ventilation-induced lung …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) represent a
continuum of injury that may arise from a number of primary insults. Localised injury may …