Peptide-based fibrous biomaterials: some things old, new and borrowed

DN Woolfson, MG Ryadnov - Current opinion in chemical biology, 2006 - Elsevier
Bioinspired fibrous materials that span the nano-to-meso scales have potentially broad
applications in nanobiotechnology; for instance, as scaffolds in 3D cell culture and tissue …

Engineered and designed peptide-based fibrous biomaterials

CE MacPhee, DN Woolfson - Current Opinion in Solid State and Materials …, 2004 - Elsevier
Our increasing understanding of peptide and protein folding and assembly raises new
possibilities for engineering novel self-assembling supramolecular structures and bio …

Building fibrous biomaterials from α‐helical and collagen‐like coiled‐coil peptides

DN Woolfson - Peptide Science: Original Research on …, 2010 - Wiley Online Library
Over the decade and a half, interest has soared in the development of peptide‐based
biomaterials and their potential applications in biotechnology. This review outlines the …

More than just bare scaffolds: towards multi-component and decorated fibrous biomaterials

DN Woolfson, ZN Mahmoud - Chemical Society Reviews, 2010 - pubs.rsc.org
We are entering a new phase in biomaterials research in which rational design is being
used to produce functionalised materials tailored to specific applications. As is evident from …

Designer self-assembling peptide nanofiber biological materials

CAE Hauser, S Zhang - Chemical Society Reviews, 2010 - pubs.rsc.org
Scientists and bioengineers have dreamed of designing materials from the bottom up with
the finest detail and ultimate control at the single molecular level. The discovery of a class of …

[PDF][PDF] Assembly pathway of a designed α-helical protein fiber

EHC Bromley, KJ Channon, PJS King, ZN Mahmoud… - Biophysical journal, 2010 - cell.com
Interest in the design of peptide-based fibrous materials is growing because it opens
possibilities to explore fundamental aspects of peptide self-assembly and to exploit the …

Bioorthogonal dual functionalization of self-assembling peptide fibers

ZN Mahmoud, SB Gunnoo, AR Thomson, JM Fletcher… - Biomaterials, 2011 - Elsevier
The ability to modify peptide-and protein-based biomaterials selectively under mild
conditions and in aqueous buffers is essential to the development of certain areas of …

Fibrillar peptide gels in biotechnology and biomedicine

JP Jung, JZ Gasiorowski… - Peptide Science: Original …, 2010 - Wiley Online Library
Peptides, peptidomimetics, and peptide derivatives that self‐assemble into fibrillar gels have
received increasing interest as synthetic extracellular matrices for applications in 3D cell …

Engineering the morphology of a self-assembling protein fibre

MG Ryadnov, DN Woolfson - Nature materials, 2003 - nature.com
Biological assemblies provide inspiration for the development of new materials for a variety
of applications,. Our ability to realize this potential, however, is hampered by difficulties in …

Higher-order assembly of collagen peptides into nano-and microscale materials

DE Przybyla, J Chmielewski - Biochemistry, 2010 - ACS Publications
The triple-helical structure of collagen peptides has recently been harnessed as a subunit in
the higher-order assembly of unique biomaterials. Specific assembly signals have been …