A tool for biomarker discovery in the urinary proteome: a manually curated human and animal urine protein biomarker database

C Shao, M Li, X Li, L Wei, L Zhu, F Yang, L Jia… - Molecular & Cellular …, 2011 - ASBMB
Urine is an important source of biomarkers. A single proteomics assay can identify hundreds
of differentially expressed proteins between disease and control samples; however, the …

Applications of urinary proteomics in biomarker discovery

C Shao, Y Wang, YH Gao - Science China life sciences, 2011 - Springer
Urine is an important source of biomarkers. This article reviews current advances, major
challenges, and future prospects in the field of urinary proteomics. Because the practical …

A comprehensive map of the human urinary proteome

A Marimuthu, RN O'Meally, R Chaerkady… - Journal of proteome …, 2011 - ACS Publications
The study of the human urinary proteome has the potential to offer significant insights into
normal physiology as well as disease pathology. The information obtained from such studies …

A comprehensive analysis and annotation of human normal urinary proteome

M Zhao, M Li, Y Yang, Z Guo, Y Sun, C Shao, M Li… - Scientific reports, 2017 - nature.com
Biomarkers are measurable changes associated with the disease. Urine can reflect the
changes of the body while blood is under control of the homeostatic mechanisms; thus, urine …

Practical points in urinary proteomics

V Thongboonkerd - Journal of proteome research, 2007 - ACS Publications
During the proteomic era, one of the most rapidly growing areas in biomedical research is
biomarker discovery, particularly using proteomic technologies. Urinary proteomics has …

Comprehensive analysis of individual variation in the urinary proteome revealed significant gender differences*[S]

C Shao, M Zhao, X Chen, H Sun, Y Yang, X Xiao… - Molecular & Cellular …, 2019 - ASBMB
Disease biomarkers are the measurable changes associated with a pathophysiological
process. Without homeostatic control, urine accumulates systematic changes in the body …

Urine in clinical proteomics

S Decramer, AG de Peredo, B Breuil, H Mischak… - Molecular & cellular …, 2008 - ASBMB
Urine has become one of the most attractive biofluids in clinical proteomics as it can be
obtained non-invasively in large quantities and is stable compared with other biofluids. The …

Human urine proteome: a powerful source for clinical research

L Zou, W Sun - Urine Proteomics in Kidney Disease Biomarker …, 2015 - Springer
As noninvasive and easily available biological fluid, urine is becoming an ideal sample for
proteomic study. In recent years, researchers endeavored in profiling urinary proteome and …

An integrated proteomic and peptidomic assessment of the normal human urinome

A Di Meo, I Batruch, AG Yousef, MD Pasic… - Clinical Chemistry and …, 2017 - degruyter.com
Background: Urine represents an ideal source of clinically relevant biomarkers as it contains
a large number of proteins and low molecular weight peptides. The comprehensive …

Urinary proteomics: towards biomarker discovery, diagnostics and prognostics

V Thongboonkerd - Molecular bioSystems, 2008 - pubs.rsc.org
During recent years, the proteomics field has moved onward to clinical applications,
particularly for biomarker discovery, diagnostics and prognostics of human diseases. The …