Prescribing ANtiDepressants Appropriately (PANDA): a cluster randomized controlled trial in primary care

E Muskens, R Eveleigh, P Lucassen, C van Weel… - BMC Family …, 2013 - Springer
Background Inappropriate use of antidepressants (AD), defined as either continuation in the
absence of a proper indication or continuation despite the lack of therapeutic efficacy …

[HTML][HTML] Withdrawal of unnecessary antidepressant medication: a randomised controlled trial in primary care

R Eveleigh, E Muskens, P Lucassen, P Verhaak… - BJGP open, 2018 - bjgpopen.org
Background Antidepressant use has increased exponentially in recent decades, mostly due
to long continuation. Aim To assess the effectiveness of a tailored recommendation to …

Patients' attitudes to discontinuing not-indicated long-term antidepressant use: barriers and facilitators

R Eveleigh, A Speckens, C van Weel… - Therapeutic …, 2019 - journals.sagepub.com
Background: Long-term antidepressant use has increased exponentially, though this is not
always according to guidelines. Our previous randomized controlled trial (RCT) showed that …

Predicting intentions towards long-term antidepressant use in the management of people with depression in primary care: A longitudinal survey study

R Dewar-Haggart, I Muller, F Bishop, A Geraghty… - medRxiv, 2024 - medrxiv.org
Background Over the last two decades, antidepressant prescribing in the UK has increased
considerably, due to an increased number of people staying on antidepressants for longer …

Self-reported reasons for reducing or stopping antidepressant medications in primary care: thematic analysis of the diamond longitudinal study

A Coe, J Gunn, S Fletcher, E Murray… - Primary Health Care …, 2023 - cambridge.org
Background: Current treatment guidelines advise that the deprescribing of antidepressants
should occur around 6 months post-remission of symptoms. However, this is not routinely …

Should I, can I, dare I? Patients' view on stopping long-term antidepressant use, a qualitative study

E Van Leeuwen, S Anthierens, ML van Driel… - Acta Clinica …, 2022 - Taylor & Francis
Background and aim The rise in long-term antidepressant use is concerning. Long-term
antidepressant (AD) use, much longer than recommended by guidelines, can result in risk of …

Compliance with antidepressants in a primary care setting, 1: beyond lack of efficacy and adverse events

K Demyttenaere, P Enzlin, W Dewé… - Journal of clinical …, 2001 - psychiatrist.com
Background: Treatment guidelines recommend antidepressant treatment be continued for at
least 6 months to ensure maximal improvement and to prevent relapse. Naturalistic studies …

Evidence review: efficacy and effectiveness of antidepressant treatment in primary care

GE Simon - General hospital psychiatry, 2002 - Elsevier
This review considers evidence for the efficacy of pharmacotherapy among primary care
patients with depressive disorders and reviews knowledge regarding the effectiveness of …

Health care professional barriers and facilitators to discontinuing antidepressant use: A systematic review and thematic synthesis

E Van Leeuwen, E Maund, C Woods, H Bowers… - Journal of Affective …, 2024 - Elsevier
Introduction Long-term antidepressant (AD) use, much longer than recommended, is very
common and can lead to potential harms. Objective To investigate the existing literature on …

The monitoring of longer term prescriptions of antidepressants: observational study in a primary care setting

JE Sinclair, LS Aucott, K Lawton, IC Reid… - Family …, 2014 - academic.oup.com
Background. There is little evidence to guide the frequency of review for patients taking
antidepressants in the longer term. Objectives. To measure the frequency with which …