Discovery of ingenane and jatrophane diterpenoids from Euphorbia esula as inhibitors of RANKL-induced osteoclastogenesis
Abstract Two new ingenane diterpenoids (1–2), four new jatrophane diterpenoids (3–6), and
seven known analogues (7–13), were isolated from the 95% ethanol extract of Euphorbia …
seven known analogues (7–13), were isolated from the 95% ethanol extract of Euphorbia …
Jatrophane Diterpenoids from Euphorbia esula as Inhibitors of RANKL-Induced Osteoclastogenesis
Eighteen new jatrophane diterpenoids, euphoesulatins A–R (1–18), and three known
diterpenoids (19–21) were isolated from Euphorbia esula. Compounds 1–7, 14, and 18 …
diterpenoids (19–21) were isolated from Euphorbia esula. Compounds 1–7, 14, and 18 …
Discovery of diverse diterpenoid scaffolds from Euphorbia antiquorum and their activity against RANKL-induced osteoclastogenesis
ZY Yin, Y Dai, P Hua, ZJ Sun, YF Cheng, SH Yuan… - Bioorganic …, 2019 - Elsevier
Seven new diterpenoids, euphorantones A–D (1, 3, 6, and 10), 8, 12, 13-epi-3, 7, 12-O-
triacetyl-8-O-(2-methylbutanoyl)-ingol (9), 8, 12, 13-epi-3, 12-O-diacetyl-7-O-benzoyl-8 …
triacetyl-8-O-(2-methylbutanoyl)-ingol (9), 8, 12, 13-epi-3, 12-O-diacetyl-7-O-benzoyl-8 …
Identification and structural modification of ent-rosane diterpenoids from Euphorbia milii inhibiting RANKL-induced osteoclastogenesis
X Peng, S Liu, Y Zhang, J Xu, Q Gu - Bioorganic Chemistry, 2024 - Elsevier
Phytochemical study on Euphorbia milii, a common ornamental plant, resulted in the
identification of thirteen new ent-rosane diterpenoids (1–13), three new ent-atisane …
identification of thirteen new ent-rosane diterpenoids (1–13), three new ent-atisane …
Euphoesulatin A prevents osteoclast differentiation and bone loss via inhibiting RANKL-induced ROS production and NF-κB and MAPK signal pathways
Abstract Euphoesulatin A (Eup A), a new jatrophane diterpenoid isolated from the Euphorbia
esula L.(Euphorbiaceae), was reported to inhibit RANKL-induced osteoclastogenesis …
esula L.(Euphorbiaceae), was reported to inhibit RANKL-induced osteoclastogenesis …
Diverse diterpenoids and sesquiterpenoids from Siegesbeckia pubescens and their activity against RANKL-induced osteoclastogenesis
Phytochemical investigation of the aerial parts of Siegesbeckia pubescens led to seventeen
diterpenoids (1–17) and twelve sesquiterpenoids (18–29). Their structures were varied …
diterpenoids (1–17) and twelve sesquiterpenoids (18–29). Their structures were varied …
Diterpenoids from the aerial parts of Flueggea acicularis and their activity against RANKL-induced osteoclastogenesis
Compounds 1–11 were isolated from the aerial parts of Flueggea acicularis Croizz Webster,
including three new rearranged clesistanthane diterpenoids fluacinoids AC (1–3) and five …
including three new rearranged clesistanthane diterpenoids fluacinoids AC (1–3) and five …
Euphomilones A and B, ent-Rosane Diterpenoids with 7/5/6 and 5/7/6 Skeletons from Euphorbia milii
Three highly modified ent-rosane diterpenoids, euphomilones A (1) and B (2) and
euphomianol A (3), were isolated from the aerial parts of Euphorbia milii. The structures …
euphomianol A (3), were isolated from the aerial parts of Euphorbia milii. The structures …
Triterpenoids from Euphorbia pulcherrima with inhibitory effects on osteoclastogenesis
Abstract Three new compounds (1–3), euphorimaoid A (1), euphorimaoid B (2), 1α-hydroxy-
3β-acetoxy-olean-9, 12-diene (3), two firstly isolated natural products 3β-acetyloxy-olean-13 …
3β-acetoxy-olean-9, 12-diene (3), two firstly isolated natural products 3β-acetyloxy-olean-13 …
Effect of echinalkamide identified from Echinacea purpurea (L.) Moench on the inhibition of osteoclastogenesis and bone resorption
Plant cell cultures have been exploited to provide stable production and new secondary
metabolites for better pharmacological activity. Fractionation of adventitious root cultures of …
metabolites for better pharmacological activity. Fractionation of adventitious root cultures of …