Comparing the predictive value of multiple cognitive, affective, and motor tasks after rodent traumatic brain injury

Z Zhao, DJ Loane, MG Murray, BA Stoica… - Journal of …, 2012 - liebertpub.com
Controlled cortical impact injury (CCI) is a widely-used, clinically-relevant model of traumatic
brain injury (TBI). Although functional outcomes have been used for years in this model, little …

Motor and cognitive function evaluation following experimental traumatic brain injury

ST Fujimoto, L Longhi, KE Saatman… - … & biobehavioral reviews, 2004 - Elsevier
Traumatic brain injury (TBI) in humans may cause extensive sensorimotor and cognitive
dysfunction. As a result, many TBI researchers are beginning to assess behavioral …

Criteria to define mild, moderate, and severe traumatic brain injury in the mouse controlled cortical impact model

L Siebold, A Obenaus, R Goyal - Experimental neurology, 2018 - Elsevier
Traumatic brain injury (TBI) is a major health concern in the United States resulting in a
substantial number of hospitalizations and in a broad spectrum of symptoms and disabilities …

The effect of injury severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in mice

PM Washington, PA Forcelli, T Wilkins… - Journal of …, 2012 - liebertpub.com
Traumatic brain injury (TBI) can cause a broad array of behavioral problems including
cognitive and emotional deficits. Human studies comparing neurobehavioral outcomes after …

Deficits in novelty exploration after controlled cortical impact

AK Wagner, BA Postal, SD Darrah, X Chen… - Journal of …, 2007 - liebertpub.com
Experimental models of traumatic brain injury (TBI) have been utilized to characterize the
behavioral derangements associated with brain trauma. Several studies exist characterizing …

The revised neurobehavioral severity scale (NSS‐R) for rodents

AM Yarnell, ES Barry, A Mountney… - Current protocols in …, 2016 - Wiley Online Library
Motor and sensory deficits are common following traumatic brain injury (TBI). Although
rodent models provide valuable insight into the biological and functional outcomes of TBI …

Clinical relevance of behavior testing in animal models of traumatic brain injury

SR Shultz, SJ McDonald, F Corrigan… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) is a leading cause of morbidity worldwide, with patients often
suffering from consequences such as cognitive deficits, social abnormalities, anxiety …

Neurobehavioral assessment of outcome following traumatic brain injury in rats: an evaluation of selected measures

RJ Hamm - Journal of neurotrauma, 2001 - liebertpub.com
Neurobehavioral assessment of outcome has played an integral part in traumatic brain
injury (TBI) research. Given the fundamental role of neurobehavioral measurement, it is …

Validation of a controlled cortical impact model of head injury in mice

HJ HANNAY, Z FELDMAN, P PHAN… - Journal of …, 1999 - liebertpub.com
ABSTRACT A controlled cortical impact model of head injury was validated with mice. Mice
were randomly assigned to moderate head injury, mild head injury, and sham injury groups …

Dissociable long-term cognitive deficits after frontal versus sensorimotor cortical contusions

MD Lindner, MA Plone, CK Cain, B Frydel… - Journal of …, 1998 - liebertpub.com
Cognitive deficits are the most enduring and disabling sequelae of human traumatic brain
injury (TBI), but quantifying the magnitude, duration, and pattern of cognitive deficits …