Objective To determine whether a baseline (random) cortisol concentration< 25 μg/dL in
patients with septic shock was a better discriminator of adrenal insufficiency than the …

Recently, there has been renewed interest in corticosteroid therapy for patients with septic
shock. The cortisol response to a tetracosactide stimulation test, otherwise known as a short …

The recent demonstration of the significant reduction in mortality in patients with septic shock
treated with adjunctive glucocorticoids combined with fludrocortisone and the effectiveness …

Adrenal insufficiency has been reported with increased frequency in critical ill patients with
sepsis and other inflammatory states. Its incidence varies widely depending on the criteria …

Background: There is considerable global uncertainty on the role of low-dose corticosteroids
in septic shock, which translates into variations in prescribing practices. Objective: To …

OBJECTIVE To highlight the role of relative adrenal insufficiency in the outcome of critically
ill patients with sepsis and systematically review the literature regarding the use of …

Sir: Bouachour et al. reported in a recent issue of Intensive Care Medicine [1] a prospective
cohort of 40 consecutive patients in septic shock in whom adrenal gland function was …

Objective: Corticosteroid regimens that stimulate both mineralocorticoid and glucocorticoid
pathways consistently reverse vasopressor-dependent hypotension in septic shock but have …

Methods: Between July, 2005, and June, 2006, 82 patients were prospectively enrolled in
the study if they met the criteria of septic shock and relative adrenal insufficiency. All patients …

Context: Adrenal dysfunction remains a controversial issue in critical care. The long-stay
intensive care unit (ICU) population may be at increased risk of adrenal insufficiency …