Porous silicon nanoparticles (pSiNPs) are a promising nanocarrier system for drug delivery
owing to their biocompatibility, biodegradability, and non-inflammatory nature. Here, we …

The largest obstacle to the use of oligonucleotides as therapeutic agents is the delivery of
these large and negatively charged biomolecules through cell membranes into intracellular …

In this study, thermally hydrocarbonised porous silicon nanoparticles (THCpSiNPs) capped
with polyethylenimine (PEI) were fabricated, and their potential for small interfering RNA …

Porous silicon nanoparticles as a novel platform in gene therapy, have shown to be an
efficient vehicle for the delivery of nucleic acids in cells. For the first time, a family of porous …

Aims: Porous silicon nanoparticles (pSiNPs) with tunable pore size are biocompatible and
biodegradable, suggesting that they are suitable biomaterials as vehicles for drug delivery …

Peptide nucleic acids (PNAs) are a class of artificial oligonucleotide mimics that have
garnered much attention as precision biotherapeutics for their efficient hybridization …

Porous silicon nanoparticles (PSiNPs) as nanocarriers for anticancer drug delivery have an
important potential for cancer treatments, thus the development of PSiNPs-based delivery …

Poly-L-lysine-modified silica nanoparticles (PMS-NP) is a novel nonviral vector for gene
delivery, which can efficiently deliver plasmid DNA and antisense oligonucleotides into …

Porous silicon nanoparticles (PSiNPs) as drug nanocarriers have been widely applied in the
field of nanomedicine. However, a major challenge in PSiNP-based drug delivery systems is …

Improving the intratumoral distribution of anticancer agents remains the critical challenge for
developing efficient cancer chemotherapy. Luminescent porous silicon nanoparticles …