Conjunctival malignant melanoma in D enmark: epidemiology, treatment and prognosis with special emphasis on tumorigenesis and genetic profile

AC Larsen - 2016 - Wiley Online Library
Conjunctival malignant melanoma is a rare disease associated with considerable mortality.
Most published data have been based on case reports or series of referred patients. In …

BRAF mutations in conjunctival melanoma: investigation of incidence, clinicopathological features, prognosis and paired premalignant lesions

AC Larsen, C Dahl, CM Dahmcke… - Acta …, 2016 - Wiley Online Library
Purpose To investigate incidence, clinicopathological features and prognosis of BRAF‐
mutated conjunctival melanoma in Denmark. Furthermore, to determine BRAF mutations in …

A retrospective review of conjunctival melanoma presentation, treatment, and outcome and an investigation of features associated with BRAF mutations

AC Larsen, CM Dahmcke, C Dahl… - JAMA …, 2015 - jamanetwork.com
Importance Large studies investigating clinical presentation and treatment in primary
conjunctival melanoma (CM) are rare. Clinicopathological characteristics ofBRAF-mutated …

Conjunctival melanoma and melanocytic intra-epithelial neoplasia

N Kenawy, SL Lake, SE Coupland, BE Damato - Eye, 2013 - nature.com
The rarity of conjunctival melanoma has impeded progress in the management of patients
with this cancer; however, much progress has occurred in recent years. Primary acquired …

Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas

KG Griewank, H Westekemper, R Murali, M Mach… - Clinical Cancer …, 2013 - AACR
Purpose: Conjunctival melanoma is a rare but potentially deadly tumor of the eye. Despite
effective local therapies, recurrence and metastasis remain frequent. Once the tumor has …

NF1 mutations in conjunctival melanoma

SL Scholz, I Cosgarea, D Süßkind, R Murali… - British Journal of …, 2018 - nature.com
Background Conjunctival melanoma is a potentially deadly eye tumour. Despite effective
local therapies, tumour recurrence and metastasis remain frequent. The genetics of …

[PDF][PDF] Molecular biology in conjunctival melanoma and the relationship to mucosal melanoma

LH Mikkelsen - 2020 - researchgate.net
Conjunctival melanoma is a rare malignancy of melanocytes located in the conjunctiva–the
mucosal membrane covering the eye. The course of disease is often uncomplicated with …

Genetic biomarkers in melanoma of the ocular region: what the medical oncologist should know

KF Bol, M Donia, S Heegaard, JF Kiilgaard… - International journal of …, 2020 - mdpi.com
Melanoma of the ocular region (ocular melanoma) comprises about 5% of all patients with
melanoma and covers posterior uveal melanoma, iris melanoma, and conjunctival …

MicroRNA expression profile in conjunctival melanoma

AC Larsen, LH Mikkelsen, R Borup… - … & visual science, 2016 - iovs.arvojournals.org
Purpose: Conjunctival melanoma (CM) is a rare disease associated with considerable
mortality. As opposed to cutaneous melanoma, the epigenetic mechanisms involved in the …

Prognostic factors for conjunctival melanoma: a study in ethnic Chinese patients

X Sheng, S Li, Z Chi, L Si, C Cui, L Mao… - British Journal of …, 2015 - bjo.bmj.com
Background/objective In patients with conjunctival melanomas, surgery is the first choice of
treatment, but no standard adjuvant therapy has been established. In this study, we …