Nebivolol Ameliorates Nitric Oxide–Deficient Hypertension
LA Fortepiani, MC Ortíz, NM Atucha… - The Scientific World …, 2002 - hindawi.com
Nebivolol is a new selective beta 1-adrenoceptor antagonist with nitric oxide (NO)–releasing
properties. In the present study we have analyzed whether nebivolol affects the …
properties. In the present study we have analyzed whether nebivolol affects the …
Characterization of nitric oxide release by nebivolol and its metabolites
A Maffei, C Vecchione, A Aretini… - American journal of …, 2006 - academic.oup.com
Background: Nebivolol is a selective β1-adrenergic receptor antagonist that causes a direct
vasodilator effect attributed to the action on vascular nitric oxide (NO). This study aimed to …
vasodilator effect attributed to the action on vascular nitric oxide (NO). This study aimed to …
Effect of nebivolol on renal nitric oxide availability and tubular function in patients with essential hypertension
FH Mose, JM Jensen, S Therwani… - British Journal of …, 2015 - Wiley Online Library
Aims Nebivolol is a selective β1‐receptor antagonist with vasodilating properties. In patients
with essential hypertension, we tested the hypothesis that nebivolol increases systemic and …
with essential hypertension, we tested the hypothesis that nebivolol increases systemic and …
Protective actions of nebivolol on chronic nitric oxide synthase inhibition-induced hypertension and chronic kidney disease in the rat: a comparison with angiotensin II …
NC Moningka, T Tsarova, JM Sasser… - Nephrology Dialysis …, 2012 - academic.oup.com
Background. Nitric oxide (NO) deficiency contributes to chronic kidney disease (CKD)
progression and hypertension. The β-blocker, nebivolol (N), also enhances NO production …
progression and hypertension. The β-blocker, nebivolol (N), also enhances NO production …
Experimental evidences of nitric oxide‐dependent vasodilatory activity of nebivolol, a third‐generation β‐blocker
L Ignarro - Blood Pressure, 2004 - Taylor & Francis
Nebivolol is a new and selective β 1‐adrenergic receptor antagonist whose haemodynamic
profile is different from that of classical β‐blockers. The blood pressure lowering effects of …
profile is different from that of classical β‐blockers. The blood pressure lowering effects of …
Nitric oxide mechanisms of nebivolol
A Maffei, G Lembo - Therapeutic advances in cardiovascular …, 2009 - journals.sagepub.com
β-blockers are among the most widely used drugs in the prevention and treatment of
cardiovascular disease, although they are associated with increased peripheral resistance …
cardiovascular disease, although they are associated with increased peripheral resistance …
Nitric-oxide-mediated relaxations in salt-induced hypertension: effect of chronic β1-selective receptor blockade
F Cosentino, S Bonetti, R Rehorik, M Eto… - Journal of …, 2002 - journals.lww.com
Background Nebivolol is a new β 1-selective adrenergic receptor antagonist with a direct
vasorelaxant effect that involves activation of the l-arginine–nitric oxide (NO) pathway …
vasorelaxant effect that involves activation of the l-arginine–nitric oxide (NO) pathway …
The cellular mechanisms involved in the vasodilator effect of nebivolol on the renal artery
Nebivolol is known as a highly selective β1-adrenoceptor antagonist. Based on the reported
vasodilator effect of nebivolol, we examined the cellular mechanisms by which the drug …
vasodilator effect of nebivolol, we examined the cellular mechanisms by which the drug …
Nebivolol: A Highly Selective β1‐Adrenergic Receptor Blocker That Causes Vasodilation by Increasing Nitric Oxide
S Gupta, HM Wright - Cardiovascular therapeutics, 2008 - Wiley Online Library
Nebivolol (Bystolic®) is a cardioselective beta 1 (β1)‐adrenergic receptor blocker with
endothelium‐dependent vasodilating properties. The endothelium‐dependent relaxation …
endothelium‐dependent vasodilating properties. The endothelium‐dependent relaxation …
Nebivolol reverses endothelial dysfunction in essential hypertension: a randomized, double-blind, crossover study
N Tzemos, PO Lim, TM MacDonald - Circulation, 2001 - Am Heart Assoc
Background Vascular endothelial dysfunction may predict future atherosclerosis. Hence, an
antihypertensive agent that reverses endothelial dysfunction and lowers blood pressure …
antihypertensive agent that reverses endothelial dysfunction and lowers blood pressure …