Efficacy and tolerability of nebivolol compared with other antihypertensive drugs: a meta-analysis
LM Van Bortel, F Fici, F Mascagni - American Journal of Cardiovascular …, 2008 - Springer
Background and objective Lowering BP to normal levels without quality of life deterioration
is the most important means of reducing cardiovascular risk. Recent studies have …
is the most important means of reducing cardiovascular risk. Recent studies have …
Nebivolol induces calcium-independent signaling in endothelial cells by a possible β-adrenergic pathway
W Gosgnach, C Boixel, N Névo… - Journal of …, 2001 - journals.lww.com
Nebivolol is a highly selective β 1-adrenoreceptor-blocking agent with a peculiar
pharmacodynamic profile. It has peripheral acute vasodilating properties that are mediated …
pharmacodynamic profile. It has peripheral acute vasodilating properties that are mediated …
A review of the safety and efficacy of nebivolol in the mildly hypertensive patient
C John - Vascular health and risk management, 2007 - Taylor & Francis
Nebivolol is a third generation beta-blocker, which can be distinguished from other beta-
blockers by its hemodynamic profile. It combines beta-adrenergic blocking activity with a …
blockers by its hemodynamic profile. It combines beta-adrenergic blocking activity with a …
Haemodynamic effects and pharmacokinetics of oral d-and l-nebivolol in hypertensive patients
A Himmelmann, T Hedner, E Snoeck… - European journal of …, 1996 - Springer
Objective: Nebivolol is a selective β 1-adrenergic receptor blocker possessing an ancillary
vasodilating effect. The objective of the present study was to study the haemodynamic and …
vasodilating effect. The objective of the present study was to study the haemodynamic and …
[HTML][HTML] A review of nebivolol pharmacology and clinical evidence
J Fongemie, E Felix-Getzik - Drugs, 2015 - Springer
Nebivolol is a highly selective β 1-adrenergic receptor antagonist with a pharmacologic
profile that differs from those of other drugs in its class. In addition to cardioselectivity …
profile that differs from those of other drugs in its class. In addition to cardioselectivity …
Therapeutic dose of nebivolol, a nitric oxide-releasing β-blocker, reduces atherosclerosis in cholesterol-fed rabbits
F de Nigris, FP Mancini, ML Balestrieri, R Byrns… - Nitric Oxide, 2008 - Elsevier
Nitric oxide (NO) exerts a plethora of vascular beneficial effects. The NO-releasing β-blocker
nebivolol is a racemic mixture of d/l-enantiomers that displays negative inotropic as well as …
nebivolol is a racemic mixture of d/l-enantiomers that displays negative inotropic as well as …
P-251: Nebivolol in the treatment of patients with stage 1 and stage 2 hypertension: Results of a randomized, double-blind, placebo-controlled study
RJ Weiss, MA Weber, AA Carr… - American Journal of …, 2005 - search.proquest.com
The purpose of this study was to establish the antihypertensive efficacy and safety of
nebivolol-a novel, highly selective β 1 blocker with nitric-oxide mediated vasodilatory effects …
nebivolol-a novel, highly selective β 1 blocker with nitric-oxide mediated vasodilatory effects …
Antihypertensive agents prevent nephrosclerosis and left ventricular hypertrophy induced in rats by prolonged inhibition of nitric oxide synthesis
N Akuzawa, T Nakamura, T Kurashina… - American journal of …, 1998 - academic.oup.com
We investigated the ability of the angiotensin converting enzyme (ACE) inhibitor imidapril
hydrochloride, and of the calcium channel blocker amlodipine besilate, to prevent …
hydrochloride, and of the calcium channel blocker amlodipine besilate, to prevent …
Protective effects of nebivolol and reversal of endothelial dysfunction in diabetes associated with hypertension
A Georgescu, D Popov, E Dragan, E Dragomir… - European journal of …, 2007 - Elsevier
This study aims to decipher the potential effects of nebivolol in prevention and/or regression
of renal artery dysfunction in diabetes associated with hypertension. Renal arteries were …
of renal artery dysfunction in diabetes associated with hypertension. Renal arteries were …
Beta blockers, nitric oxide, and cardiovascular disease
PM Vanhoutte, Y Gao - Current opinion in pharmacology, 2013 - Elsevier
The third generation β-blockers possess important ancillary properties besides inhibiting β-
adrenoceptors. Among them, nebivolol activates nitric oxide synthase (NOS). Nebivolol and …
adrenoceptors. Among them, nebivolol activates nitric oxide synthase (NOS). Nebivolol and …