Distribution of iduronate 2-sulphate residues in heparan sulphate. Evidence for an ordered polymeric structure

JE Turnbull, JT Gallagher - Biochemical journal, 1991 - portlandpress.com
The structure of human skin fibroblast heparan sulphate has been examined by
depolymerization with heparinase, which specifically cleaves highly sulphated …

The distribution of 2-acetamido-2-deoxy-D-glucose residues in mammalian heparins

JA Cifonelli, J King - Carbohydrate Research, 1972 - Elsevier
Highly purified, beef-mucosa heparin, shown to be free of contaminating
glycosaminoglycans and having relatively high proportions of linkage-region components …

Mapping and quantification of the major oligosaccharide components of heparin

RJ Linhardt, KG Rice, YS Kim, DL Lohse… - Biochemical …, 1988 - portlandpress.com
A new method of determining the oligosaccharide composition of commercial
glycosaminoglycan heparin is described in which heparin was first depolymerized using …

Biosynthesis of heparin. Substrate specificity of heparosan N-sulfate D-glucuronosyl 5-epimerase.

I Jacobsson, U Lindahl, JW Jensen, L Rodén… - Journal of Biological …, 1984 - Elsevier
The substrate specificity of heparosan N-sulfate D-glucuronosyl 5-epimerase from a mouse
mastocytoma was examined to determine the effects of N-acetyl and O-sulfate groups on …

The disaccharide composition of heparins and heparan sulfates

Y Guo, HE Conrad - Analytical biochemistry, 1989 - Elsevier
Heparin and heparan sulfate can be cleaved selectively at their N-sulfated glucosamine
residues by direct treatment with nitrous acid at pH 1.5. These polymers can also be cleaved …

[HTML][HTML] Liver heparan sulfate structure. A novel molecular design

M Lyon, JA Deakin, JT Gallagher - Journal of Biological Chemistry, 1994 - Elsevier
The structure of rat liver heparan sulfate (HS) has been investigated using a combination of
(a) chain scission with specific reagents,(b) disaccharide compositional analysis, and (c) …

Distribution of sulfated glycosaminoglycans in the animal kingdom: widespread occurrence of heparin-like compounds in invertebrates

GF Medeiros, A Mendes, RAB Castro, EC Baú… - … et Biophysica Acta (BBA …, 2000 - Elsevier
Sulfated glycosaminoglycans were isolated from 23 species of 13 phyla of invertebrates and
characterized by their electrophoretic migration in three different buffer systems coupled with …

Structural differences and the presence of unsubstituted amino groups in heparan sulphates from different tissues and species

T Toida, H Yoshida, H Toyoda, I Koshiishi… - Biochemical …, 1997 - portlandpress.com
This study presents a comparison of heparan sulphate chains isolated from various porcine
and bovine tissues. 1H-NMR spectroscopy (500 MHz) was applied for structural and …

[引用][C] Structure of heparin and heparin fragments

B Casu - Annals of the New York Academy of Sciences, 1989 - Wiley Online Library
Like most glycosaminoglycans, heparin is an alternating copolymer of a uronic acid and an
amino sugar, and its structure is commonly represented by its prevalent disaccharide …

Molecular distinctions between heparan sulphate and heparin. Analysis of sulphation patterns indicates that heparan sulphate and heparin are separate families of N …

JT Gallagher, A Walker - Biochemical Journal, 1985 - portlandpress.com
Heparan sulphate and heparin are chemically related alpha β-linked glycosaminoglycans
composed of alternating sequences of glucosamine and uronic acid. The amino sugars may …