Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological …
The design of randomised controlled trials (RCTs) should incorporate characteristics (such
as concealment of randomised allocation and blinding of participants and personnel) that …
as concealment of randomised allocation and blinding of participants and personnel) that …
A systematic review of comparisons of effect sizes derived from randomised and non-randomised studies.
RR MacLehose, BC Reeves, IM Harvey… - Health technology …, 2000 - europepmc.org
Background There is controversy about the value of evidence about the effectiveness of
healthcare interventions from non-randomised study designs. Advocates for quasi …
healthcare interventions from non-randomised study designs. Advocates for quasi …
Empirical evidence of study design biases in randomized trials: systematic review of meta-epidemiological studies
Objective To synthesise evidence on the average bias and heterogeneity associated with
reported methodological features of randomized trials. Design Systematic review of meta …
reported methodological features of randomized trials. Design Systematic review of meta …
Alternatives to randomisation in the evaluation of public health interventions: design challenges and solutions
CP Bonell, J Hargreaves, S Cousens… - … of Epidemiology & …, 2011 - jech.bmj.com
Background There has been a recent increase in interest in alternatives to randomisation in
the evaluation of public health interventions. We aim to describe specific scenarios in which …
the evaluation of public health interventions. We aim to describe specific scenarios in which …
The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions.
SH Downs, N Black - Journal of epidemiology & community health, 1998 - jech.bmj.com
OBJECTIVE: To test the feasibility of creating a valid and reliable checklist with the following
features: appropriate for assessing both randomised and non-randomised studies; provision …
features: appropriate for assessing both randomised and non-randomised studies; provision …
Evaluating non-randomised intervention studies.
OBJECTIVES: To consider methods and related evidence for evaluating bias in non-
randomised intervention studies. DATA SOURCES: Systematic reviews and methodological …
randomised intervention studies. DATA SOURCES: Systematic reviews and methodological …
Health intervention research: Understanding research design and methods
S Sidani - 2014 - torrossa.com
In an era characterized by an emphasis on evidence-informed practice, research plays a
central role in helping us understand human conditions, behaviors, and emerging problems; …
central role in helping us understand human conditions, behaviors, and emerging problems; …
Should meta-analyses of interventions include observational studies in addition to randomized controlled trials? A critical examination of underlying principles
Some authors argue that systematic reviews and meta-analyses of intervention studies
should include only randomized controlled trials because the randomized controlled trial is a …
should include only randomized controlled trials because the randomized controlled trial is a …
A study of target effect sizes in randomised controlled trials published in the Health Technology Assessment journal
JC Rothwell, SA Julious, CL Cooper - Trials, 2018 - Springer
Background When designing a randomised controlled trial (RCT), an important
consideration is the sample size required. This is calculated from several components; one …
consideration is the sample size required. This is calculated from several components; one …
Assessing the generalizability of randomized trial results to target populations
EA Stuart, CP Bradshaw, PJ Leaf - Prevention Science, 2015 - Springer
Recent years have seen increasing interest in and attention to evidence-based practices,
where the “evidence” generally comes from well-conducted randomized trials. However …
where the “evidence” generally comes from well-conducted randomized trials. However …