In mammalian ovaries, a fixed population of primordial follicles forms during the perinatal
stage and the oocytes contained within are arrested at the dictyate stage of meiotic …

The intracellular levels of cAMP play a critical role in the meiotic arrest of mammalian
oocytes. However, it is debated whether this second messenger is produced endogenously …

Fully-grown mammalian oocytes within healthy preovulatory follicles are arrested in the first
meiotic prophase until the gonadotropins surge in vivo. However, the means by which …

Cyclic AMP (cAMP) is one of the key regulators of the resumption of oocyte meiosis (oocyte
maturation) in several mammalian species. In this study we have examined the role for …

The involvement of cyclic AMP (cAMP) in mammalian oocyte maturation was assessed
using cultures of rabbit cumulus–oocyte complexes and in-vitro perfused rabbit ovaries …

The possible mediatory role of cAMP in the induction of oocyte maturation by luteinizing
hormone (LH) is not yet clear since evidence for both inhibitory and stimulatory actions of the …

The second messenger cyclic adenosine 5′ monophosphate (cAMP) has been implicated
in controlling meiotic maturation. To date, there have been no direct measurements of cAMP …

Intact ovarian follicles and isolated oocytes were cultured for 30 sec to 18 hr in the presence
of gonadotrophins, and the cyclic AMP content in the follicle and oocyte was measured. The …

In mammalian ovaries, the balance between dormancy and activation of primordial follicles
determines the female fecundity and endocrine homeostasis. Recently, several functional …

ABSTRACT Cyclic adenosine 3'-5'monophosphate (cAMP) acts as a second messenger for
various pituitary hormones. The mode of involvement of cAMP in the regulation of meiotic …