Bovine oocytes are arrested at the prophase of first meiotic cell cycle. Meiosis resumes in
oocytes of pre‐ovulatory follicles upon LH surge. However, oocytes from secondary follicles …

Background Recent results indicate a key role for cyclic guanosine monophosphate (cGMP)
in the regulation of oocyte meiotic arrest in preovulatory mammalian follicles. The aim of our …

Forskolin, a diterpene that activates rapidly adenylate cyclase activity in several somatic cell
systems, prevents spontaneous meiotic maturation of denuded mouse oocytes (ED50 of …

During the development of oocyte-granulosa cell complexes from preantral follicles in vitro,
oocytes grow and acquire competence to undergo germinal vesicle breakdown (GVB). In the …

In the growing follicle, communication between the oocyte and its surrounding follicular cells
is essential for normal oocyte and follicular development. Maturation of the fully grown …

Mammalian oocytes grow and undergo meiosis within ovarian follicles. Fully grown oocytes
are arrested at the first meiotic prophase by a mural granulosa origin “arrester” until a surge …

The effects of the putative maturation inhibitor in porcine follicular fluid on
gonadotropinstimulated reversal of cyclic adenosine monophosphate (cAMP)‐maintained …

Acetylcholine rapidly lowered the intracellular levels of cyclic AMP in stage 5 and 6 Xenopus
laevis oocytes. Acetylcholine alone did not induce oocyte maturation, though it did …

Mature antral follicles were removed from the ovaries of pregnant mare serum gonadotropin
(PMSG)-primed hamsters at proestrus prior to the LH surge. Following various incubation …

Experiments were performed to determine if elevation of cumulus cell cAMP results in an
increase in mouse oocyte cAMP while the heterologous gap junctions were intact. Both …