It is common practice to interpret the effect of a given drug on a given effector system in
terms of an interaction between the drug and a specific receptive substance or receptor of …

The concept of receptors, first introduced by Langley (1878, 1905), has become extremely
important in pharmacology. The law of mass action can be applied to the drug-receptor …

It is now almost a decade since the first attempts to isolate and characterize pharmacological
receptors were made. In the intervening years, increasing numbers of investigators have …

Much has been written about the quantitative aspects of drug antagonism and many
attempts have been made to account for the facts in terms of the generally accepted theory …

This book is designed to meet the modern need for a better understanding of drug-receptor
interaction as applied to the gathering and interpretation of dose-response data. It is an …

It is not my purpose to advocate any particular model for drug action as being the truth. And,
a fortiori the particular values of parameters used here in numerical examples are chosen for …

* Raleigh Fitkin-Paul Morgan Memorial Hospital v. Anderson, 42 Page 1 NATURE VOL. 231
MAY 14 1971 * Steptoe, PC, Edwards, RG, and Purdy, JM, Nature, 229, 132 (1971). 7 Gardner …

According to the usual drug-receptor model, developed by Clark, Gaddum, and Stephenson,
one can determine drug-receptor dissociation equilibriun constants and relative efficacies …

Receptor Classification Although receptor classifications have often originated from
observations with agonists, there appears to be widespread agreement that the safest …

By RAYMOND P. AHLQUIST t this moment in time it is appropriate to A review briefly the
status of the adrenergic receptor. The nomenclature of CY and p receptors introduced by this …