[HTML][HTML] The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection

S Pons, S Fodil, E Azoulay, L Zafrani - Critical care, 2020 - Springer
In severe SARS-CoV-2 infections, emerging data including recent histopathological studies
have emphasized the crucial role of endothelial cells (ECs) in vascular dysfunction …

[HTML][HTML] Endotheliitis and endothelial dysfunction in patients with COVID-19: its role in thrombosis and adverse outcomes

W Mosleh, K Chen, SE Pfau, A Vashist - Journal of Clinical Medicine, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV2), emerging in Wuhan, China and …

[HTML][HTML] Covid-19: the rollercoaster of fibrin (ogen), d-dimer, von willebrand factor, p-selectin and their interactions with endothelial cells, platelets and erythrocytes

C Grobler, SC Maphumulo, LM Grobbelaar… - International journal of …, 2020 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), also known as coronavirus
disease 2019 (COVID-19)-induced infection, is strongly associated with various …

Severe COVID-19 infection associated with endothelial activation

R Escher, N Breakey, B Lämmle - Thrombosis research, 2020 - thrombosisresearch.com
Mounting evidence supports the strong prognostic importance of D-dimers and the impact of
coagulopathy in COVID-19 patients [1, 2, 3]. We would like to emphasize the significance of …

Contribution of the von Willebrand factor/ADAMTS13 imbalance to COVID-19 coagulopathy

R Seth, TAJ McKinnon… - American Journal of …, 2022 - journals.physiology.org
The 2019 coronavirus disease (COVID-19) is the disease caused by SARS-CoV-2 infection.
Although this infection has been shown to affect the respiratory system, a high incidence of …

[HTML][HTML] Oxidative stress-induced endothelial dysfunction and decreased vascular nitric oxide in COVID-19 patients

V Montiel, I Lobysheva, L Gerard, M Vermeersch… - …, 2022 - thelancet.com
Background SARS-CoV-2 targets endothelial cells through the angiotensin-converting
enzyme 2 receptor. The resulting endothelial injury induces widespread thrombosis and …

[HTML][HTML] Extended coagulation profile of children with Long Covid: a prospective study

L Di Gennaro, P Valentini, S Sorrentino, MA Ferretti… - Scientific reports, 2022 - nature.com
Emerging data suggests that endotheliopathy changes can be associated with post covid
condition (PCC) in adults. Research on the matter in children is lacking. We analyzed an …

Endotheliopathy is induced by plasma from critically ill patients and associated with organ failure in severe COVID-19

A Rauch, A Dupont, J Goutay, M Caplan, S Staessens… - Circulation, 2020 - Am Heart Assoc
COVID-19 at the Lille University Hospital between March 30, 2020, and April 8, 2020, in
convalescent patients with COVID-19 (n= 6 from the 12 patients in the ICU) sampled after …

[HTML][HTML] Cellular and molecular mechanisms in COVID-19 coagulopathy: role of inflammation and endotheliopathy

R Cacciola, E Gentilini Cacciola, V Vecchio… - Journal of Thrombosis …, 2022 - Springer
Abstract Introduction Coronavirus 2 (CoV-2) infection or coronavirus disease 2019 (COVID-
19) is frequently associated with microvascular thrombosis. The microthrombosis in COVID …

Association of neutrophil activation, more than platelet activation, with thrombotic complications in coronavirus disease 2019

E Petito, E Falcinelli, U Paliani, E Cesari… - The Journal of …, 2021 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 infection is associated with
hypercoagulability, which predisposes to venous thromboembolism (VTE). We analyzed …