Intrauterine growth retardation (IUGR) has been linked to later development of type 2
diabetes in adulthood. Human studies indicate that individuals who were growth retarded at …

In pregnancy complicated by placental insufficiency (PI) and intrauterine growth restriction
(IUGR), the fetus near term has reduced basal and glucose-stimulated insulin …

We measured the impact of chronic late gestation hypoglycemia on pancreatic islet structure
and function to determine the cause of decreased insulin secretion in this sheep model of …

There is ample evidence that an adverse intrauterine environment has harmful
consequences for health in later life. Maternal diabetes and experimentally induced …

Placental insufficiency is associated with reduced supply of amino acids to the fetus and
leads to intrauterine growth restriction (IUGR). IUGR fetuses are characterized by lower …

Intrauterine growth restriction (IUGR) increases the risk for metabolic disease and diabetes,
although the developmental origins of this remain unclear. We measured glucose …

Intrauterine growth restriction increases adult metabolic disease risk with evidence to
suggest that suboptimal conditions in utero can have transgenerational effects. We …

Intrauterine growth retardation has been linked to the development of type 2 diabetes in later
life. The mechanisms underlying this phenomenon are unknown. We have developed a …

Intrauterine growth restriction (IUGR) has been defined in several ways, but in general
describes a condition in which the fetus exhibits poor growth in utero. This complication of …

Objective Mothers fed a high-fat (HF) diet can cause different adverse alterations in their
offspring. The study aimed to verify the pancreatic islet structure and insulin-signaling …