A family history of diabetes predisposes to gestational diabetes mellitus (GDM). We
hypothesized that female offspring of rats with pre-gestational diabetes will develop GDM, a …

Aims Intra-uterine growth restriction (IUGR) followed by accelerated postnatal growth is
associated with an increased risk of obesity and type 2 diabetes. We aimed to determine …

Type 2 diabetes is characterized by islet dysfunction resulting in hyperglycemia, which can
then lead to further deterioration in islet function. A possible mechanism for hyperglycemia …

Intrauterine growth-restricted (IUGR) fetal sheep have increased hepatic glucose production
(HGP) that is resistant to suppression during a hyperinsulinemic-isoglycemic clamp (insulin …

Inadequate β-cell mass can lead to insulin insufficiency and diabetes. During times of
prolonged metabolic demand for insulin, the endocrine pancreas can respond by increasing …

The maintenance of normal carbohydrate metabolism requires an intricate interplay
between insulin action and insulin secretion. Type 2 diabetes usually results from a …

Aims To compare the insulin sensitivity and secretion indices of pregnant Bangladeshi
women with GDM and normal glucose tolerance (NGT). Methods This cross sectional study …

Obesity and gestational diabetes during pregnancy have multiple short-and long-term
consequences for both mother and child. One common feature of pregnancies complicated …

Intrauterine growth restriction (IUGR) caused by placental insufficiency is one of the most
common and complex problems in perinatology, with no known cure. In pregnancies …

OBJECTIVE Alteration of placental structure may influence fetal overgrowth and
complications of maternal diabetes. We examined the placenta in a cohort of offspring of …