DNA methylation plays a key role in neural cell fate and provides a molecular link between
early life stress and later-life behavioral phenotypes. Here, studies that combine …

Genetic and environmental factors interact during sensitive periods early in life to influence
mental health and disease via epigenetic processes such as DNA methylation. However, it …

Psychological stress can increase the risk of a wide range of negative health outcomes.
Studies have been completed to determine if DNA methylation changes occur in the human …

A growing body of research has documented associations between adverse childhood
environments and DNA methylation, highlighting epigenetic processes as potential …

While it is well-known that stress during development and adulthood can confer long-term
neurobiological and behavioral consequences, investigators have only recently begun to …

Animal and humans exposed to stress early in life are more likely to suffer from long-term
behavioral, mental health, metabolic, immune, and cardiovascular health consequences …

Adverse early-life experiences (ELA) affect a majority of the world's children. Whereas the
enduring impact of ELA on cognitive and emotional health is established, there are no tools …

Epigenetic mechanisms, such as DNA methylation (DNAm), have gained increasing
attention as potential biomarkers and mechanisms underlying risk for neurodevelopmental …

Background Recent findings in neuroimaging and epigenetics offer important insights into
brain structures and biological pathways of altered gene expression associated with …

Advances in epigenetic methodologies have deepened theoretical explanations of
mechanisms linking early life stress (ELS) and disease outcomes and suggest promising …