Recent studies have suggested that apoptosis is a key phenomenon in the chemopreventive
action of nonsteroidal antiinflammatory drugs (NSAIDs), which exhibit cancer‐preventive …

Mice bearing LP07 lung adenocarcinoma show some characteristics that are similar to those
present in patients with NSCLC. LP07 tumor‐bearing mice develop the paraneoplastic …

Non‐steroidal anti‐inflammatory drugs (NSAIDs) and specific inhibitors of cyclooxygenase
(COX)‐2, are therapeutic groups widely used for the treatment of pain, inflammation and …

Many reports have demonstrated that non-steroidal anti-inflammatory drugs (NSAIDs)
suppress malignant transformation and tumor growth, and some NSAIDs are expected to be …

Non-steroidal anti-inflammatory drugs (NSAIDs) are emerging as novel chemopreventive
agents against a variety of cancers owing to their capability in blocking the tumor …

Initiation of malignancy is dependent upon the basic ratio of cell proliferation and apoptosis.
Many molecular proteins and pathways are responsible for the imbalance of proliferation …

Nitric oxide-releasing aspirin (NO-aspirin) represents a novel class of promising
chemopreventive agents. Unlike conventional nonsteroidal anti-inflammatory drugs, NO …

The inducible isoforms of nitric oxide synthase (iNOS) and cyclooxygenase (COX-2) are
overexpressed in colonic tumors of humans, as well as in colon tumors that develop in rats …

Humans are exposed to a wide range of nitrogen-containing compounds and nitrosating
agents, such as nitrite, nitrate and nitrogen oxides (NOx), that can react in vivo to form …

Heading Abstract Purpose. Although NSAIDs (nonsteroidal antiinflammatory drugs) appear
to be effective in the prevention and treatment of prostate cancer, very little information exists …