Role of chemokine systems in cancer and inflammatory diseases

H Li, M Wu, X Zhao - MedComm, 2022 - Wiley Online Library
Chemokines are a large family of small secreted proteins that have fundamental roles in
organ development, normal physiology, and immune responses upon binding to their …

Chemokines in cancer related inflammation

P Allavena, G Germano, F Marchesi… - Experimental cell …, 2011 - Elsevier
Chemokines are key players of the cancer-related inflammation. Chemokine ligands and
receptors are downstream of genetic events that cause neoplastic transformation and are …

The chemokine system in cancer biology and therapy

A Mantovani, B Savino, M Locati, L Zammataro… - Cytokine & growth factor …, 2010 - Elsevier
Chemokines are a key component of cancer-related inflammation. Chemokines and
chemokine receptors are downstream of genetic events that cause neoplastic transformation …

Chemokines in cancer development and progression and their potential as targeting molecules for cancer treatment

N Mukaida, S Sasaki, T Baba - Mediators of inflammation, 2014 - Wiley Online Library
Chemokines were initially identified as bioactive substances, which control the trafficking of
inflammatory cells including granulocytes and monocytes/macrophages. Moreover …

Chemokines in cancer

MT Chow, AD Luster - Cancer immunology research, 2014 - AACR
Chemokines are chemotactic cytokines that control the migration of cells between tissues
and the positioning and interactions of cells within tissue. The chemokine superfamily …

Chemokines: key players in cancer

M Arya, HRH Patel, M Williamson - Current medical research and …, 2003 - Taylor & Francis
Chemokines are a family of low molecular weight (8-10kDa) pro-inflammatory cytokines,
which bind to G-protein coupled receptors. Their primary function is chemoattraction and …

Chemokines and their receptors: multifaceted roles in cancer progression and potential value as cancer prognostic markers

HTT Do, CH Lee, J Cho - Cancers, 2020 - mdpi.com
Chemokines are chemotactic cytokines that mediate immune cell chemotaxis and lymphoid
tissue development. Recent advances have indicated that chemokines and their cognate …

Chemokines and chemokine receptors: new insights into cancer-related inflammation

G Lazennec, A Richmond - Trends in molecular medicine, 2010 - cell.com
Chemokines are involved in cellular interactions and tropism in situations frequently
associated with inflammation. Recently, the importance of chemokines and chemokine …

Chemokines modulate immune surveillance in tumorigenesis, metastasis, and response to immunotherapy

AE Vilgelm, A Richmond - Frontiers in immunology, 2019 - frontiersin.org
Chemokines are small secreted proteins that orchestrate migration and positioning of
immune cells within the tissues. Chemokines are essential for the function of the immune …

The complexity of targeting chemokines to promote a tumor immune response

M Strazza, A Mor - Inflammation, 2020 - Springer
Immunotherapeutic treatment strategies greatly extend patient survival following malignant
disease across a wide range of tumor types, including even those with metastatic disease …