Viscosin-like lipopeptides from frog skin bacteria inhibit Aspergillus fumigatus and Batrachochytrium dendrobatidis detected by imaging mass spectrometry and …

C Martin H, R Ibáñez, LF Nothias, CA Boya P… - Scientific reports, 2019 - nature.com
Amphibian populations worldwide have declined and in some cases become extinct due to
chytridiomycosis, a pandemic disease caused by the fungus Batrachochytrium …

Recent methods for discovering novel bioactive metabolites, specifically antimicrobial agents, from marine‐associated micro‐organisms

AM Sedeek, MM Ismail, TR Elsayed… - Letters in Applied …, 2022 - academic.oup.com
Marine micro‐organisms are a promising source for novel natural compounds with many
medical and biotechnological applications. Here, we demonstrate limitations and recent …

Fraunhofer to mine Sanofi microbial collection

JL Fox - Nature Biotechnology, 2014 - go.gale.com
Paris-based Sanofi and the Fraunhofer Institute for Molecular Biology and Applied Ecology
(IME) in January announced a joint effort to explore natural products as leads for developing …

Diversity and distribution of bacteria producing known secondary metabolites

J Nappi, E Soldi, S Egan - Microbial ecology, 2019 - Springer
There is an increasing interest in the utilisation of marine bioactive compounds as novel
biopharmaceuticals and agrichemicals; however, little is known about the environmental …

Recent developments in antibacterial drug discovery: microbe-derived natural products–from collection to the clinic

JA Leeds, EK Schmitt, P Krastel - Expert opinion on investigational …, 2006 - Taylor & Francis
The pharmaceutical industry has historically relied on nature to provide compounds for
antibacterial drug discovery. In recent years, several pharmaceutical companies have …

Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides

DD Nguyen, AV Melnik, N Koyama, X Lu… - Nature …, 2016 - nature.com
Pseudomonads are cosmopolitan microorganisms able to produce a wide array of
specialized metabolites. These molecules allow Pseudomonas to scavenge nutrients, sense …

Antimicrobial activity in culturable gut microbial communities of springtails

V Agamennone, D Roelofs… - Journal of applied …, 2018 - academic.oup.com
Aims The rise of antibiotic resistance pushes the pharmaceutical industry to continually
search for substances with new structures and novel mechanisms of action. Many …

Web of microbes (WoM): a curated microbial exometabolomics database for linking chemistry and microbes

SM Kosina, AM Greiner, RK Lau, S Jenkins, R Baran… - BMC microbiology, 2018 - Springer
Background As microbiome research becomes increasingly prevalent in the fields of human
health, agriculture and biotechnology, there exists a need for a resource to better link …

Composition and metabolic potential of microbiomes associated with mesopelagic animals from Monterey Canyon

C Breusing, KJ Osborn, PR Girguis… - ISME …, 2022 - academic.oup.com
There is growing recognition that microbiomes play substantial roles in animal eco-
physiology and evolution. To date, microbiome research has largely focused on terrestrial …

Rapid, field-deployable method for collecting and preserving plant metabolome for biochemical and functional characterization

SA Skubel, V Dushenkov, BL Graf, Q Niu, A Poulev… - PLoS …, 2018 - journals.plos.org
Study of plant metabolome is a growing field of science that catalogs vast biochemical and
functional diversity of phytochemicals. However, collecting and storing samples of plant …