Genotoxicity induced by fine urban air particulate matter in the macrophages cell line RAW 264.7

A Poma, T Limongi, C Pisani, V Granato, P Picozzi - Toxicology in vitro, 2006 - Elsevier
Recent studies support a participation of fine airborne particulate matter (PM) with an
aerodynamic diameter less than 2.5 μm in the effects of air pollutants on health. Particulate …

Physicochemical characteristics and biological activities of seasonal atmospheric particulate matter sampling in two locations of Paris

A Baulig, JJ Poirault, P Ausset, R Schins… - … science & technology, 2004 - ACS Publications
Fine particulate matter present in urban areas seems to be incriminated in respiratory
disorders. The aim of this study was to relate physicochemical characteristics of PM2. 5 …

DIESEL particulate exposed macrophages alter endothelial cell expression of eNOS, iNOS, MCP1, and glutathione synthesis genes

CS Weldy, HW Wilkerson, TV Larson, JA Stewart… - Toxicology in Vitro, 2011 - Elsevier
There is considerable debate regarding inhaled diesel exhaust particulate (DEP) causing
impairments in vascular reactivity. Although there is evidence that inhaled particles can …

Diesel exhaust particles exert acute effects on airway inflammation and function in murine allergen provocation models

M Hao, S Comier, M Wang, JJ Lee, A Nel - Journal of allergy and clinical …, 2003 - Elsevier
BACKGROUND: Epidemiologic studies show that sudden surges in ambient particulate
matter (PM) levels can trigger acute asthma exacerbations. Although diesel exhaust …

Subchronic effects of nasally instilled diesel exhaust particulates on the nasal and airway epithelia in mice

K Yoshizaki, JM Brito, AC Toledo… - Inhalation …, 2010 - Taylor & Francis
Diesel exhaust is the major source of ultrafine particles released during traffic-related
pollution. Subjects with chronic respiratory diseases are at greater risk for exacerbations …

Diesel exhaust particles enhance T‐cell activation in severe asthmatics

E Mamessier, A Nieves, D Vervloet, A Magnan - Allergy, 2006 - Wiley Online Library
Prevalence of asthma is increasing in westernized countries. Epidemiological studies
showed the impact of traffic pollution on the triggering of asthma symptoms and …

Effect of exposure to diesel exhaust particles on the susceptibility of the lung to infection.

V Castranova, JY Ma, HM Yang… - Environmental …, 2001 - ehp.niehs.nih.gov
There are at least three mechanisms by which alveolar macrophages play a critical role in
protecting the lung from bacterial or viral infections: production of inflammatory cytokines that …

In vitro pulmonary and vascular effects induced by different diesel exhaust particles

R Bengalli, A Zerboni, S Marchetti, E Longhin, M Priola… - Toxicology letters, 2019 - Elsevier
Diesel exhaust particles (DEP) are responsible for both respiratory and cardiovascular
effects. However many questions are still unravelled and the mechanisms behind the health …

The dual effect of the particulate and organic components of diesel exhaust particles on the alteration of pulmonary immune/inflammatory responses and metabolic …

JYC Ma, JKH Ma - Journal of Environmental Science and Health …, 2002 - Taylor & Francis
Exposure to diesel exhaust particles (DEP) is an environmental and occupational health
concern. This review examines the cellular actions of the organic and the particulate …

Diesel Exhaust (DE)–Induced Cytokine Expression in Human Bronchial Epithelial Cells: A Study with a New Cell Exposure System to Freshly Generated DE In Vitro

S Abe, H Takizawa, I Sugawara… - American Journal of …, 2000 - atsjournals.org
We devised a new in vitro cell exposure system to freshly generated diesel exhaust (DE),
different from conventional in vitro culture systems, to examine the effects of DE on human …