Carbon dots nanozyme for anti-inflammatory therapy via scavenging intracellular reactive oxygen species

C Dong, X Ma, Y Huang, Y Zhang… - Frontiers in Bioengineering …, 2022 - frontiersin.org
Developing an efficient antioxidant for anti-inflammatory therapy via scavenging reactive
oxygen species (ROS) remains a great challenge owing to the insufficient activity and …

Carbon dots as nanocatalytic medicine for anti-inflammation therapy

B Kong, T Yang, F Cheng, Y Qian, C Li, L Zhan… - Journal of Colloid and …, 2022 - Elsevier
Aberrant reactive oxygen species (ROS) generation is one of the crucial mediators in the
pathogenesis of inflammation. So, the development of nanocatalytic medicine to catalyze the …

Inhibition of oxidative stress in vivo through enzyme-like activity of carbon dots

C Dong, S Wang, M Ma, P Wei, Y Chen, A Wu… - Applied Materials …, 2021 - Elsevier
Oxidative stress is a huge challenge to human health, and effective agents for resisting this
adverse effect are remains limited recently. Here, an excellent enzyme-like activity of carbon …

Carbon dots derived from citric acid and glutathione as a highly efficient intracellular reactive oxygen species scavenger for alleviating the lipopolysaccharide-induced …

H Wang, ML Zhang, Y Ma, B Wang… - … Applied Materials & …, 2020 - ACS Publications
Reactive oxygen species (ROSs), acting as functionalized molecules in intracellular enzyme
reactions and intercellular communication of immune response, play vital roles in biological …

Integrating Pt nanoparticles with carbon nanodots to achieve robust cascade superoxide dismutase-catalase nanozyme for antioxidant therapy

Y Zhang, W Gao, Y Ma, L Cheng, L Zhang, Q Liu… - Nano Today, 2023 - Elsevier
Nanozymes, nanomaterials with intrinsic enzyme mimetic activity, have emerged and been
used in a broad range of applications yet are constrained with limited catalytic efficiency …

Nanozymes regulate redox homeostasis in ROS-related inflammation

Q Li, Y Liu, X Dai, W Jiang, H Zhao - Frontiers in Chemistry, 2021 - frontiersin.org
Reactive oxygen species (ROS), in moderate amounts, play an essential role in regulating
different physiological functions in organisms. However, increased amounts of ROS may …

Metal-free multifunctional nanozymes mimicking endogenous antioxidant system for acute kidney injury alleviation

J Liu, X Huang, F Zhang, X Luo, W Yu, C Li… - Chemical Engineering …, 2023 - Elsevier
Cellular redox homeostasis is highly dependent on endogenous antioxidant systems,
including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) …

Carbon dot nanozymes as free radicals scavengers for the management of hepatic ischemia-reperfusion injury by regulating the liver inflammatory network and …

H Geng, J Chen, K Tu, H Tuo, Q Wu, J Guo… - Journal of …, 2023 - Springer
Background Hepatic ischemia-reperfusion injury (HIRI) is a pathophysiological process
during liver transplantation, characterized by insufficient oxygen supply and subsequent …

Versatile carbon dots with superoxide dismutase-like nanozyme activity and red fluorescence for inflammatory bowel disease therapeutics

Y Ma, J Zhao, L Cheng, C Li, X Yan, Z Deng, Y Zhang… - Carbon, 2023 - Elsevier
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease
(CD), is a chronic and recurrent disease that seriously affects the life quality of patients …

Rational design and biological application of antioxidant nanozymes

R Tian, J Xu, Q Luo, C Hou, J Liu - Frontiers in chemistry, 2021 - frontiersin.org
Nanozyme is a type of nanostructured material with intrinsic enzyme mimicking activity,
which has been increasingly studied in the biological field. Compared with natural enzymes …