Discovery of biomarker candidates within disease by protein profiling: principles and concepts
G Marko-Varga, H Lindberg, CG Löfdahl… - Journal of proteome …, 2005 - ACS Publications
Proteins and peptides present within clinical samples represent a valuable library of
information regarding the ongoing processes within cells and tissues in health and disease …
information regarding the ongoing processes within cells and tissues in health and disease …
Clinical proteomics in lung diseases
N Waldburg, T Kähne, A Reisenauer, C Röcken… - … -Research and Practice, 2004 - Elsevier
Proteomics is a relatively new approach for understanding the pathology and pathogenesis
of various diseases. It has also been used for characterizing the modifications in protein …
of various diseases. It has also been used for characterizing the modifications in protein …
Proteomics: current techniques and potential applications to lung disease
Proteomics aims to study the whole protein content of a biological sample in one set of
experiments. Such an approach has the potential value to acquire an understanding of the …
experiments. Such an approach has the potential value to acquire an understanding of the …
Proteomics analysis in lung cancer: challenges and opportunities
T Kikuchi, DP Carbone - Respirology, 2007 - Wiley Online Library
Recent technological developments in proteomic analysis are bringing us new insights into
the molecular classification of tumours. Although proteomic analysis in cancer profiling is still …
the molecular classification of tumours. Although proteomic analysis in cancer profiling is still …
Advances and challenges in liquid chromatography-mass spectrometry-based proteomics profiling for clinical applications
Recent advances in proteomics technologies provide tremendous opportunities for
biomarker-related clinical applications; however, the distinctive characteristics of human …
biomarker-related clinical applications; however, the distinctive characteristics of human …
A proteomic primer for the clinician
Y Guo, Z Fu, JE Van Eyk - Proceedings of the American Thoracic …, 2007 - atsjournals.org
Proteomics is a rapidly developing field and it opens new horizons in many research areas
of life sciences. In the field of medicine, proteomics promises to accelerate the discovery of …
of life sciences. In the field of medicine, proteomics promises to accelerate the discovery of …
Proteomics and disease the challenges for technology and discovery
G Marko-Varga, TE Fehniger - Journal of proteome research, 2004 - ACS Publications
The study of protein expression within distinct clinical disease settings is a major focus of
biomedical research today. Powerful technology tools can now define the specific protein …
biomedical research today. Powerful technology tools can now define the specific protein …
Informatics platform for global proteomic profiling and biomarker discovery using liquid chromatography-tandem mass spectrometry
D Radulovic, S Jelveh, S Ryu, TG Hamilton… - Molecular & cellular …, 2004 - ASBMB
We have developed an integrated suite of algorithms, statistical methods, and computer
applications to support large-scale LC-MS-based gel-free shotgun profiling of complex …
applications to support large-scale LC-MS-based gel-free shotgun profiling of complex …
Achieving in-depth proteomics profiling by mass spectrometry
NG Ahn, JB Shabb, WM Old, KA Resing - ACS Chemical Biology, 2007 - ACS Publications
Proteomics addresses the important goal of determining the chemistry and composition of
proteins in biological samples. Mass-spectrometry-based strategies have been highly …
proteins in biological samples. Mass-spectrometry-based strategies have been highly …
Proteomic analysis of lung biopsies: Differential protein expression profile between peritumoral and tumoral tissue
P Alfonso, M Catalá, ML Rico‐Morales… - …, 2004 - Wiley Online Library
The cellular proteome shows a dynamic profile and is subjected to changes in response to
various stimuli and disease progression. Lung cancer remains the leading cause of cancer …
various stimuli and disease progression. Lung cancer remains the leading cause of cancer …