Subacute and chronic proteomic and phosphoproteomic analyses of a mouse model of traumatic brain injury at two timepoints and comparison with chronic traumatic …
Repetitive mild traumatic brain injury (r-mTBI) is the most widespread type of brain trauma
worldwide. The cumulative injury effect triggers long-lasting pathological and molecular …
worldwide. The cumulative injury effect triggers long-lasting pathological and molecular …
Repeated mild traumatic brain injuries induce persistent changes in plasma protein and magnetic resonance imaging biomarkers in the rat
A single mild traumatic brain injury (mTBI) typically causes only transient symptoms, but
repeated mTBI (RmTBI) is associated with cumulative and chronic neurological …
repeated mTBI (RmTBI) is associated with cumulative and chronic neurological …
Unbiased proteomic approach identifies unique and coincidental plasma biomarkers in repetitive mTBI and AD pathogenesis
The relationship between repetitive mild traumatic brain injury (r-mTBI) and Alzheimer's
disease (AD) is well-recognized. However, the precise nature of how r-mTBI leads to or …
disease (AD) is well-recognized. However, the precise nature of how r-mTBI leads to or …
Quantitative proteomics reveals the dynamic pathophysiology across different stages in a rat model of severe traumatic brain injury
W Luo, Z Yang, W Zhang, D Zhou, X Guo… - Frontiers in Molecular …, 2022 - frontiersin.org
Background Severe traumatic brain injury (TBI) has become a global health problem and
causes a vast worldwide societal burden. However, distinct mechanisms between acute and …
causes a vast worldwide societal burden. However, distinct mechanisms between acute and …
Functional Analysis of the Cortical Transcriptome and Proteome Reveal Neurogenesis, Inflammation, and Cell Death after Repeated Traumatic Brain Injury In vivo
CS Dunn, LA Ferreira, SM Venier, SF Ali… - Neurotrauma …, 2022 - liebertpub.com
The pathological effects of repeated traumatic brain injuries (TBIs) are largely unknown. To
gain a detailed understanding of the cortical tissue acute biological response after one or …
gain a detailed understanding of the cortical tissue acute biological response after one or …
Behavioral, blood and magnetic resonance imaging biomarkers of experimental mild traumatic brain injury
Repeated mild traumatic brain injuries (mTBI) may lead to serious neurological
consequences, especially if re-injury occurs within the period of increased cerebral …
consequences, especially if re-injury occurs within the period of increased cerebral …
[HTML][HTML] Behavioral, axonal, and proteomic alterations following repeated mild traumatic brain injury: novel insights using a clinically relevant rat model
A history of mild traumatic brain injury (mTBI) is linked to a number of chronic neurological
conditions, however there is still much unknown about the underlying mechanisms. To …
conditions, however there is still much unknown about the underlying mechanisms. To …
Identification of plasma biomarkers of TBI outcome using proteomic approaches in an APOE mouse model
The current lack of diagnostic and prognostic biomarkers for traumatic brain injury (TBI)
confounds treatment and management of patients and is of increasing concern as the TBI …
confounds treatment and management of patients and is of increasing concern as the TBI …
Early onset senescence and cognitive impairment in a murine model of repeated mTBI
N Schwab, YJ Ju, LN Hazrati - Acta Neuropathologica Communications, 2021 - Springer
Mild traumatic brain injury (mTBI) results in broad neurological symptoms and an increased
risk of being diagnosed with a neurodegenerative disease later in life. While the immediate …
risk of being diagnosed with a neurodegenerative disease later in life. While the immediate …
Repetitive mild traumatic brain injury affects inflammation and excitotoxic mRNA expression at acute and chronic time-points
The cumulative effect of mild traumatic brain injuries (mTBI) can result in chronic
neurological damage, however the molecular mechanisms underpinning this detriment …
neurological damage, however the molecular mechanisms underpinning this detriment …
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