Although highly controversial just a few years ago, the idea that G‐protein‐coupled
receptors (GPCRs) may undergo homo‐oligomerization or hetero‐oligomerization has …

G protein-coupled receptors (GPCRs) can exist as dimers or as larger oligomeric clusters
that enable intercommunication between different receptor protomers within the same …

The classical idea that G‐protein‐coupled receptors (GPCRs) function as monomeric
entities has been unsettled by the emerging concept of GPCR dimerization. Recent findings …

Recently, many G-protein-coupled receptors (GPCRs) have been demonstrated to form
constitutive dimers consisting of identical or distinct monomeric subunits. The discovery of …

Although the G protein-coupled receptor (GPCR) oligomerization has been questioned
during the last decade, under some premises the existence of a supramolecular …

G-protein-coupled receptors (GPCRs) comprise the largest family of transmembrane
receptors in the human genome that respond to a plethora of signals, including …

G-protein-coupled receptors (GPCRs) represent by far the largest class of targets for modern
drugs. Virtually all therapeutics that are directed towards GPCRs have been designed using …

The functional importance of G protein-coupled receptor (GPCR) oligomerization remains
controversial. Although obligate dimers of class C GPCRs are well accepted, the …

In the last four to five years, the view that G protein–coupled receptors (GPCRs) function as
monomeric proteins has been challenged by numerous studies, which suggests that GPCRs …

G protein-coupled receptors (GPCRs) are cell surface receptors that mediate physiological
responses to a diverse array of stimuli. GPCRs have traditionally been thought to act as …