Numerous biomaterials based on extracellular matrix-components have been developed. It
was our aim to investigate whether a hyaluronic acid–based hydrogel improves neuronal …

Object Therapies that use bioactive materials as replacement extracellular matrices may
hold the potential to mitigate the inhibition of regeneration observed after central nervous …

Our aim was to investigate axonal outgrowth from different tissue models on soft
biomaterials based on hyaluronic acid (HA). We hypothesized that HA-based hydrogels …

Objective. Demyelination that results from disease or traumatic injury, such as spinal cord
injury (SCI), can have a devastating effect on neural function and recovery. Many …

Abstract spinal cord injury (SCI) is a traumatic damage that can causes a loss of neurons
around the lesion site and resulting in locomotor and sensory deficits. Currently, there is …

In order to create an optimal microenvironment for neural regeneration in the lesion area
after spinal cord injury (SCI), we fabricated a novel scaffold composed of a hyaluronic acid …

In this work, a novel enzymatically crosslinked injectable hydrogel comprising hyaluronic
acid (HyA), dopamine (DA), and 3-(4-hydroxyphenyl) propionic acid (HPA) conjugates was …

Central nervous system (CNS) pathologies, such as stroke and spinal cord injury, remain
debilitating issues due to the inhibitory environment in the CNS. Many research works have …

Hyaluronic acid (HA) with one reactive moiety grafted to the backbone is a commonly used
matrix in tissue engineering. The addition of a second orthogonal moiety to the backbone …

Transplanting human induced pluripotent stem cells (iPSCs)-derived spinal cord progenitor
cells (SCPCs) is a promising approach to treat spinal cord injuries. However, stem cell …