The role of non-neuronal glial cells in the regulation of adipose sympathetic nerve activity
and adipocyte functions such as white adipose tissue lipid lipolysis is poorly understood …

Excessive adiposity results from an imbalance in energy homeostasis, whereby the
consequences of excessive food intake are not balanced by increased energy expenditure …

White adipocyte proliferation is a hallmark of obesity, but it largely remains a mechanistic
mystery. We and others previously demonstrated that surgical denervation of white adipose …

Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Brown adipocytes (BA) generate heat in response to sympathetic activation and are the
main site of nonshivering thermogenesis in mammals. Although most BA are located in …

Brown adipose tissue (BAT) is the site of sympathetically activated adaptive thermognenesis
during cold exposure and after hyperphagia, thereby controlling whole-body energy …

In most mammals, two types of adipose tissue, white and brown, are present. Both are able
to store energy in the form of triacylglycerols and to hydrolyze them into free fatty acids and …

Our understanding of brown adipose tissue (BAT) function in humans has increased rapidly
over the past 10 years. This is predominantly due to the development of powerful non …

To date, human studies show that brown adipose tissue (BAT) contributes a small yet highly
variable amount to overall energy expenditure. No studies have shown a decrease in body …

From mouse to man, brown adipose tissue (BAT) is a significant source of thermogenesis
contributing to the maintenance of the body temperature homeostasis during the challenge …