Irreversible electroporation: first patient experience focal therapy of prostate cancer

G Onik, B Rubinsky - Irreversible electroporation, 2010 - Springer
Irreversible electroporation (IRE) is a new non-thermal ablation modality that uses short
pulses of DC electric current to create irreversible pores in the cell membrane thus causing …

Prostate cancer treatment with Irreversible Electroporation (IRE): Safety, efficacy and clinical experience in 471 treatments

E Guenther, N Klein, S Zapf, S Weil, C Schlosser… - PloS one, 2019 - journals.plos.org
Background Irreversible Electroporation (IRE) is a novel image-guided tissue ablation
technology that induces cell death via very short but strong pulsed electric fields. IRE has …

Irreversible electroporation (IRE): a narrative review of the development of IRE from the laboratory to a prostate cancer treatment

A Blazevski, MJ Scheltema, A Amin… - BJU …, 2020 - Wiley Online Library
Introduction Whilst whole‐gland radical treatment is highly effective for prostate cancer
control, it has significant impact on quality of life and is unnecessary 'over‐treatment'in many …

Optimal parameters for the destruction of prostate cancer using irreversible electroporation

J Rubinsky, G Onik, P Mikus, B Rubinsky - The Journal of urology, 2008 - Elsevier
PURPOSE: Irreversible electroporation is a new tissue ablation technique that consists of
applying μsecond pulses of direct current to create permanent defects in the cell membrane …

The correlation between the electrode configuration and histopathology of irreversible electroporation ablations in prostate cancer patients

W Van den Bos, DM De Bruin, RR Jurhill… - World journal of …, 2016 - Springer
Purpose Irreversible electroporation (IRE) is a novel minimally invasive therapy for prostate
cancer using short electric pulses to ablate prostate tissue. The purpose of this study is to …

Irreversible electroporation: implications for prostate ablation

G Onik, P Mikus, B Rubinsky - Technology in cancer …, 2007 - journals.sagepub.com
Percutaneous prostate cryo-ablation has become an accepted treatment for primary prostate
cancer. Thermal tissue ablation based on cold, however, does have some distinct …

An evaluation of irreversible electroporation thresholds in human prostate cancer and potential correlations to physiological measurements

S Campelo, M Valerio, HU Ahmed, Y Hu… - APL …, 2017 - pubs.aip.org
Irreversible electroporation (IRE) is a non-thermal, soft tissue ablation modality 1 that has
been used to treat a variety of tumors in the liver, 2 kidneys, 3 pancreas, 4, 5 and prostate. 6 …

Focal irreversible electroporation for prostate cancer: functional outcomes and short-term oncological control

F Ting, M Tran, M Böhm, A Siriwardana… - Prostate cancer and …, 2016 - nature.com
Background: Current data on the use of irreversible electroporation (IRE) in the treatment of
prostate cancer (PCa) is limited. We aim to evaluate the safety, short-term functional and …

Histopathological outcomes after irreversible electroporation for prostate cancer: results of an ablate and resect study

W Van Den Bos, RR Jurhill, DM De Bruin… - The Journal of …, 2016 - auajournals.org
Purpose: Irreversible electroporation is a tissue ablation modality that uses high voltage
electric energy to induce an increase in cell membrane permeability. This causes …

Initial assessment of safety and clinical feasibility of irreversible electroporation in the focal treatment of prostate cancer

M Valerio, PD Stricker, HU Ahmed… - Prostate cancer and …, 2014 - nature.com
Background: To evaluate the safety and clinical feasibility of focal irreversible
electroporation (IRE) of the prostate. Methods: We assessed the toxicity profile and …