Insulin resistance is frequently associated with increased lipid content in muscle and liver.
Insulin excess stimulates tissue lipid accumulation. To examine the effects of insulin and …

Insulin resistance is associated with the circulating free fatty acid (FFA) level and
intracellular lipid content in muscle and liver. We investigated the effect of 2-wk diet and …

To examine whether and how intramyocellular lipid (IMCL) content contributes to
interindividual variation in insulin action, we studied 20 healthy men with no family history of …

An increased intramyocellular lipid (IMCL) content, as quantified by 1H-magnetic resonance
spectroscopy (1H-MRS), is associated with reduced insulin sensitivity. At present, it is …

The study aimed to analyze the effects of a short-term very low-calorie diet (VLCD) on
intramyocellular lipid (IMCL), total body fat, and insulin sensitivity in a group of obese …

Insulin resistance plays an important role in the pathogenesis of human type 2 diabetes. In
humans, a negative correlation between insulin sensitivity and intramyocellular lipid (IMCL) …

High visceral adiposity and intramyocellular lipid levels (IMCL) are both associated with the
development of type 2 diabetes. The relationship between visceral adiposity and IMCL …

Insulin resistance plays an important role in the pathogenesis of type 2 diabetes; however,
the multiple mechanisms causing insulin resistance are not yet fully understood. The aim of …

Intramyocellular lipid (IMCL) storage is considered a local marker of whole body insulin
resistance; because increments of body weight are supposed to impair insulin sensitivity …

Aims/hypothesis Impaired regulation of lipolysis and accumulation of lipid intermediates may
contribute to obesity-related insulin resistance and type 2 diabetes mellitus. We investigated …