Temporal trends in the use and comparative effectiveness of direct oral anticoagulant agents versus warfarin for nonvalvular atrial fibrillation: a Canadian population …

AYX Yu, S Malo, LW Svenson, SB Wilton… - Journal of the American …, 2017 - Am Heart Assoc
Background Direct oral anticoagulants (DOAC s) are noninferior to warfarin for stroke
prevention in atrial fibrillation (AF). We aimed to determine the population risk of stroke and …

Cost-effectiveness of oral anticoagulants for ischemic stroke prophylaxis among nonvalvular atrial fibrillation patients

A Shah, A Shewale, CJ Hayes, BC Martin - Stroke, 2016 - Am Heart Assoc
Background and Purpose—The objective of the study is to compare the cost-effectiveness of
oral anticoagulants among atrial fibrillation patients at an increased stroke risk. Methods—A …

Cost-effectiveness of edoxaban versus rivaroxaban for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF) in the US

JD Miller, X Ye, GM Lenhart, AM Farr… - ClinicoEconomics …, 2016 - Taylor & Francis
Background Understanding the value of new anticoagulation therapies compared with
existing therapies is of paramount importance in today's cost-conscious and efficiency …

Comparative effectiveness and safety of low-dose oral anticoagulants in patients with atrial fibrillation

S Perreault, A Dragomir, R Cote, A Lenglet… - Frontiers in …, 2022 - frontiersin.org
Aims: Observational studies of various dose levels of direct oral anticoagulants (DOACs) for
patients with atrial fibrillation (AF) found that a high proportion of patients received a dose …

Comparison of real-world clinical and economic outcomes in patients receiving oral anticoagulants: A retrospective claims analysis

C Karnick, A Modany, M McGraw, J Ludwig… - Journal of Managed …, 2022 - jmcp.org
BACKGROUND: Direct oral anticoagulants (DOACs) have become widely used for the
prevention of stroke in nonvalvular atrial fibrillation (AF) and for the treatment of venous …

Risks and benefits of anticoagulation in atrial fibrillation: insights from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) registry

MW Cullen, S Kim, JP Piccini Sr, JE Ansell… - … Quality and Outcomes, 2013 - Am Heart Assoc
Background—Patients with atrial fibrillation (AF) at the highest stroke risk derive the largest
benefit from oral anticoagulation (OAC). Those with the highest stroke risk have been …

[HTML][HTML] Cost-effectiveness analysis of direct oral anticoagulants vs. vitamin K antagonists in the elderly with atrial fibrillation: insights from the evidence in a real-world …

Y Wu, C Zhang, ZC Gu - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Background: In the clinical setting, the economic benefits of direct oral anticoagulants
(DOACs) in elderly patients with atrial fibrillation (AF) remain unclear. This study aimed to …

Oral Anticoagulant Use in Patients with Atrial Fibrillation at Low Risk of Stroke and Associated Bleeding Complications

AT Kefale, WM Bezabhe, GM Peterson - Journal of Clinical Medicine, 2023 - mdpi.com
Background: The use of oral anticoagulants (OACs) in patients with atrial fibrillation (AF) and
low stroke risk might cause more harm than benefit. Little attention has been given to …

Real-world direct comparison of the effectiveness and safety of apixaban, dabigatran, rivaroxaban, and warfarin in Medicare beneficiaries with atrial fibrillation

L Yang, MM Brooks, NW Glynn, Y Zhang… - The American journal of …, 2020 - Elsevier
It remains unknown whether the comparative effectiveness of direct oral anticoagulants
(DOACs) and warfarin differs between atrial fibrillation patients with and without a history of …

Effectiveness and safety of off-label dose-reduced direct oral anticoagulants in atrial fibrillation

R Arbel, R Sergienko, A Hammerman… - The American Journal of …, 2019 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) reduce the risk of stroke and
systemic embolism in patients with nonvalvular atrial fibrillation but may result in serious …