In order to clarify whether the mitochondrial dysfunction is closely related to the cell
homeostasis maintenance after particulate matter (PM 2.5) exposure, oxidative …

Nrf2 is an important transcription factor implicated in the oxidative stress response, which
has been reported to play an important role in the way by which air pollution particulate …

Exposure to ambient fine particulate matter (PM2. 5) increases the risk of respiratory
disease. Although previous mitochondrial research has provided new information about PM …

Mitochondria can be used as important biomarkers of pollutants on human health, and fine
particulate matter (PM 2.5) has been documented to cause respiratory damage. However …

More than 7 million early deaths/year are attributable to air pollution. Current health
concerns are especially focused on air pollution-derived particulate matter (PM). Although …

Introduction 3. Biological pathways of PM-induced ROS generation 4. PM perturbation of
mitochondrial function 4.1. Mechanism 1: Effects on the mitochondrial electron transfer chain …

Background Nowadays, effects of fine particulate matter (PM 2.5) are well-documented and
related to oxidative stress and pro-inflammatory response. Nevertheless, epidemiological …

Epidemiological studies revealed a sharp increase in respiratory diseases attributed to PM
2.5. However, the underlying mechanisms remain unclear. Evidence suggested …

Pulmonary fibrosis is known as an incurable lung disorder with irreversible progression of
chronic injury, myofibroblast proliferation, extracellular matrix (ECM) accumulation, and …

Rationale: Exposure to particulate matter (PM) causes lung cancer by mechanisms that are
unknown, but p53 dysfunction is implicated. Objective: We determined whether p53 is …