In the present study, we assessed the use of urinary natriuretic peptides [N-terminal proatrial
natriuretic peptide (N-ANP) and N-terminal pro-brain natriuretic peptide (N-BNP) and C-type …

Ten years ago brain natriuretic peptide (BNP), the second compound of a family of
polypeptide hormones named natriuretic peptides was identified. This peptide has great …

Neurohormonal activation in patients with heart failure is dominated by the deleterious long-
term effects of activation of the sympathetic nervous system and the renin–angiotensin …

Investigations into the mixed muscle–secretory phenotype of cardiomyocytes from the atrial
appendages of the heart led to the discovery that these cells produce, in a regulated …

BACKGROUND Plasma B-type cardiac natriuretic peptides reflect cardiac structure and
function and have proven roles in assisting in the diagnosis of acute heart failure. They are …

Atrial natriuretic peptide (ANP) and B-type natriuretic peptide decrease blood pressure and
cardiac hypertrophy by activating natriuretic peptide receptor A (NPR-A), a transmembrane …

For several decades there has been a search for an endogenous natriuretic-diuretic
hormone. As early as 1935, Peters proposed that the 'fullness' of the bloodstream may …

The cardiac natriuretic peptides, ANP (atrial natriuretic peptide) and BNP (brain natriuretic
peptide), are secreted by the heart in proportion to cardiac transmural pressures. They …

Heart has a recognized endocrine function as it produces several biologically active
substances with hormonal properties. Among these hormones, the natriuretic peptide (NP) …

Atrial and brain natriuretic peptides (ANP and BNP) are produced by the heart, and their
plasma concentrations are increased in human chronic congestive heart failure. Although …