Recent advances in stem cell biology have transformed the understanding of cell physiology
and developmental biology such that it can now play a more prominent role in the clinical …

Hematopoiesis generated from human embryonic stem cells (ES) and induced pluripotent
stem cells (iPS) are unprecedented resources for cell therapy. We compared hematopoietic …

Background Human induced pluripotent stem cells (hiPSCs) offer a renewable source of
cells for the generation of hematopoietic cells for cell-based therapy, disease modeling, and …

The development of induced pluripotent stem cell (iPSC) technology has generated
enthusiasm about the therapeutic potential of these cells for treating a variety of diseases …

Heterogeneity among induced pluripotent stem cell (iPSC) lines with regard to their gene
expression profile and differentiation potential has been described and at least partly linked …

The generation of hematopoietic stem cells (HSCs) from human pluripotent stem cells
(hPSCs) remains a major goal for regenerative medicine and disease modeling. However …

Aging, injuries, and diseases can be considered as the result of malfunctioning or damaged
cells. Regenerative medicine aims to restore tissue homeostasis by repairing or replacing …

Mesenchymal stem cells (MSCs) are adult stem cells with fibroblast-like morphology and
isolated from the bone marrow via plastic adhesion. Their multipotency and …

Reprograming somatic cells using exogenetic gene expression represents a
groundbreaking step in regenerative medicine. Induced pluripotent stem cells (iPSCs) are …

De novo generation of human hematopoietic stem cells (HSC s) from renewable cell types
has been a long sought‐after but elusive goal in regenerative medicine. Paralleling efforts to …