Background Several lines of evidence strongly suggest that agouti-related peptide (AGRP)
plays a key role in the regulation of metabolic function but ablation of the AGRP gene has no …

The Agouti-Related Protein (AgRP) is a powerful orexigenic peptide that increases food
intake when ubiquitously overexpressed or when administered centrally. AgRP-deficiency …

Agouti-related protein (AgRP) is an orexigenic neuropeptide produced by neurons in the
hypothalamic arcuate nucleus (ARC) that is a key component of central neural circuits that …

Several different neuronal populations are involved in regulating energy homeostasis.
Among these, agouti-related protein (AgRP) neurons are thought to promote feeding and …

Because α-MSH has a potent stimulatory action on hypophysiotropic TRH synthesizing
neurons in the hypothalamic paraventricular nucleus (PVN), preventing the effects of fasting …

Agouti-related peptide (AgRP) neurons of the hypothalamus play a key role in regulating
food intake and body weight, by releasing three different orexigenic molecules: AgRP; …

Abstract Agouti-related protein (AgRP), a neuropeptide abundantly expressed in the arcuate
nucleus of the hypothalamus, potently stimulates feeding and body weight gain in rodents …

The melanocortin system plays an important role in the regulation of energy homeostasis.
The Agouti-related protein (AGRP) is a natural antagonist of the action of alpha-melanocyte …

Agouti-related protein (AGRP) is a homologue of the agouti gene product and, when
overexpressed, promotes obesity. Like neuropeptide Y (NPY) messenger RNA (mRNA) …

In addition to their role in promoting feeding and obesity development, hypothalamic arcuate
agouti-related protein/neuropeptide Y (AgRP/NPY) neurons are widely perceived to be …