[HTML][HTML] Acupuncture inhibits neuroinflammation and gut microbial dysbiosis in a mouse model of Parkinson's disease

JH Jang, MJ Yeom, S Ahn, JY Oh, S Ji, TH Kim… - Brain, Behavior, and …, 2020 - Elsevier
Growing evidences show that gut microbiota is associated with the pathogenesis of
Parkinson's disease (PD) and the gut-brain axis can be promising target for the development …

Curcumin-driven reprogramming of the gut microbiota and metabolome ameliorates motor deficits and neuroinflammation in a mouse model of Parkinson's disease

C Cui, Y Han, H Li, H Yu, B Zhang, G Li - Frontiers in cellular and …, 2022 - frontiersin.org
Background Parkinson's disease (PD) is a common neurodegenerative disorder,
accompanied by motor deficits as well as gastrointestinal dysfunctions. Recent studies have …

Sodium butyrate ameliorates gut dysfunction and motor deficits in a mouse model of Parkinson's disease by regulating gut microbiota

Y Zhang, S Xu, Y Qian, C Mo, P Ai, X Yang… - Frontiers in Aging …, 2023 - frontiersin.org
Background A growing body of evidence showed that gut microbiota dysbiosis might be
associated with the pathogenesis of Parkinson's disease (PD). Microbiota-targeted …

Fecal microbiota transplantation exerts a protective role in MPTP-induced Parkinson's disease via the TLR4/PI3K/AKT/NF-κB pathway stimulated by α-synuclein

Z Zhong, W Chen, H Gao, N Che, M Xu, L Yang… - Neurochemical …, 2021 - Springer
Gut microbiota is closely related to the Parkinson's disease (PD) pathogenesis. Additionally,
aggregation of α-synuclein (α-syn) is central to PD pathogenesis. Here we identified the …

Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson's disease mice: Gut microbiota, glial reaction and TLR4/TNF-α signaling …

MF Sun, YL Zhu, ZL Zhou, XB Jia, YD Xu… - Brain, behavior, and …, 2018 - Elsevier
Parkinson's disease (PD) patients display alterations in gut microbiota composition.
However, mechanism between gut microbial dysbiosis and pathogenesis of PD remains …

Vancomycin pretreatment on MPTP-induced Parkinson's disease mice exerts neuroprotection by suppressing inflammation both in brain and gut

C Cui, H Hong, Y Shi, Y Zhou, CM Qiao… - Journal of Neuroimmune …, 2023 - Springer
A growing body of evidence implies that gut microbiota was involved in pathogenesis of
Parkinson's disease (PD), but the mechanism is still unclear. The aim of this study is to …

Probiotic Clostridium butyricum ameliorated motor deficits in a mouse model of Parkinson's disease via gut microbiota-GLP-1 pathway

J Sun, H Li, Y Jin, J Yu, S Mao, KP Su, Z Ling… - Brain, behavior, and …, 2021 - Elsevier
A connection between gut microbiota and Parkinson's disease (PD) indicates that dysbiosis
of the gut microbiota might represent a risk factor for PD. Microbiota-targeted interventions …

[HTML][HTML] Healthy human fecal microbiota transplantation into mice attenuates MPTP-induced neurotoxicity via AMPK/SOD2 pathway

Z Xie, M Zhang, Y Luo, D Jin, X Guo, W Yang… - Aging and …, 2023 - ncbi.nlm.nih.gov
Increasing evidence has shown that gut dysbacteriosis may play a crucial role in
neuroinflammation in Parkinson's disease (PD). However, the specific mechanisms that link …

Neuroprotective Effects of Bifidobacterium breve CCFM1067 in MPTP-Induced Mouse Models of Parkinson's Disease

T Li, C Chu, L Yu, Q Zhai, S Wang, J Zhao, H Zhang… - Nutrients, 2022 - mdpi.com
There is mounting evidence that the microbiota–gut–brain axis (MGBA) is critical in the
pathogenesis and progression of Parkinson's disease (PD), suggesting that probiotic …

Role of gut microbiota-derived branched-chain amino acids in the pathogenesis of Parkinson's disease: An animal study

Z Yan, F Yang, L Sun, J Yu, L Sun, Y Si… - Brain, behavior, and …, 2022 - Elsevier
Neuroinflammation caused by the disorder of gut microbiota and its metabolites is
associated with the pathogenesis of Parkinson's disease (PD). Thus, it is necessary to …