[HTML][HTML] Clinical pharmacology of fentanyl in preterm infants. A review
GM Pacifici - Pediatrics & Neonatology, 2015 - Elsevier
Fentanyl is a synthetic opioid that is very important in anesthetic practice because of its
relatively short time to peak analgesic effect and the rapid termination of action after small …
relatively short time to peak analgesic effect and the rapid termination of action after small …
Pharmacokinetics of fentanyl in neonates
DE Koehntop, JH Rodman, DM Brundage… - Anesthesia & …, 1986 - journals.lww.com
The pharmacokinetics of fentanyl were studied in fourteen neonates undergoing major
surgical procedures. Five patients were less than 1 day of age, seven ruere 1-4 days old …
surgical procedures. Five patients were less than 1 day of age, seven ruere 1-4 days old …
Individual variations in fentanyl pharmacokinetics and pharmacodynamics in preterm infants
E Norman, JM Kindblom, A Rane, AC Berg… - Acta …, 2019 - Wiley Online Library
Aim Fentanyl pharmacokinetics and pharmacodynamics are lacking in preterm infants. Our
aim was to study these and their relation with a new formulation of fentanyl 5 μg/mL for …
aim was to study these and their relation with a new formulation of fentanyl 5 μg/mL for …
Gestational age and birth weight effects on plasma clearance of fentanyl in newborn infants
E Saarenmaa, PJ Neuvonen, V Fellman - The Journal of pediatrics, 2000 - Elsevier
Objective: To provide a rational basis for the dosage of fentanyl in newborn infants by
determining clearance in the first days of life. Study design: A continuous infusion of fentanyl …
determining clearance in the first days of life. Study design: A continuous infusion of fentanyl …
Rapidly maturing fentanyl clearance in preterm neonates
S Völler, RB Flint, P Andriessen, K Allegaert… - Archives of Disease in …, 2019 - fn.bmj.com
Background Fentanyl is frequently used off-label in preterm newborns. Due to very limited
pharmacokinetic and pharmacodynamic data, fentanyl dosing is mostly based on …
pharmacokinetic and pharmacodynamic data, fentanyl dosing is mostly based on …
Analgesia and sedation in neonatal intensive care using fentanyl by continuous infusion
B Roth, C Schlünder, F Houben, M Günther… - Developmental …, 1991 - karger.com
To determine the effects of fentanyl in newborn and premature infants, we compared two
groups of 20 newborn and premature babies under artificial ventilation for severe respiratory …
groups of 20 newborn and premature babies under artificial ventilation for severe respiratory …
Advantages of fentanyl over morphine in analgesia for ventilated newborn infants after birth: a randomized trial
E Saarenmaa, P Huttunen, J Leppäluoto… - The Journal of …, 1999 - Elsevier
Objective: To compare the efficacy and adverse effects of fentanyl or morphine analgesia
during the first 2 days of life in newborn infants who underwent mechanical ventilation. Study …
during the first 2 days of life in newborn infants who underwent mechanical ventilation. Study …
Pre-and postnatal maturation are important for fentanyl exposure in preterm and term newborns: a pooled population pharmacokinetic study
Y Wu, S Völler, RB Flint, SHP Simons… - Clinical …, 2022 - Springer
Abstract Background and Objective Fentanyl is an opioid commonly used to prevent and
treat severe pain in neonates; however, its use is off label and mostly based on bodyweight …
treat severe pain in neonates; however, its use is off label and mostly based on bodyweight …
Pharmacokinetics of continuous infusion fentanyl in newborns.
ML Santeiro, J Christie, C Stromquist… - … : official journal of the …, 1997 - europepmc.org
Although fentanyl administration by continuous infusion in newborns during ventilatory
support has increased, pharmacokinetic data are lacking. Our objective was to determine …
support has increased, pharmacokinetic data are lacking. Our objective was to determine …
Pharmacokinetics of fentanyl and its derivatives in children: a comprehensive review
Fentanyl and its derivatives sufentanil, alfentanil, and remifentanil are potent opioids. A
comprehensive review of the use of fentanyl and its derivatives in the pediatric population …
comprehensive review of the use of fentanyl and its derivatives in the pediatric population …