[HTML][HTML] Early-onset gastric cancers have a different molecular expression profile than conventional gastric cancers

ANA Milne, R Carvalho, FM Morsink, AR Musler… - Modern Pathology, 2006 - Elsevier
Many studies examine the molecular genetics of gastric cancer, but few look at young
patients in particular and there is no comparison of molecular expression between early …

H19 Rises in Gastric Cancer and Exerts a Tumor-Promoting Function via miR-138/E2F2 Axis

J Yu, C Fang, Z Zhang, G Zhang, L Shi… - Cancer Management …, 2020 - Taylor & Francis
Purpose The aim of this paper was to investigate H19 expression in gastric cancer (GC) and
its effects on the biological behavior of gastric cancer cells (GCCs), and at exploring its …

[HTML][HTML] ERp29 controls invasion and metastasis of gastric carcinoma by inhibition of epithelial-mesenchymal transition via PI3K/Aktsignaling pathway

J Ye, J Huang, J Xu, Q Huang, J Wang, W Zhong, X Lin… - BMC cancer, 2017 - Springer
Background Gastric cancer (GC) accounts for the fourth most occurring malignancy and the
third major cause of cancer death. Identifying novel molecular signaling pathways …

Expression of cell-cycle regulators, cyclin E and p21WAF1/CIP1, potential prognostic markers for gastric cancer

SJ Jang, YW Park, MH Park, JD Lee, YY Lee… - European Journal of …, 1999 - Elsevier
AimsThe deregulation of cyclin, cyclin-dependent kinases (CDKs) and their inhibitors could
have a crucial role in the development of diverse human cancers. MethodsIn this study, we …

Growth pattern and expressions of cell cycle regulator proteins p53 and p21WAF1/CIP1 in early gastric carcinoma

H Noda, Y Maehara, K Irie, Y Kakeji… - … Journal of the …, 2001 - Wiley Online Library
BACKGROUND The growth pattern of early gastric carcinoma, as based on a volumetric
analysis, reflects the biologic characteristics of a tumor. The penetrating growth (Pen) type …

[HTML][HTML] Helicobacter pylori promotes VEGF expression via the p38 MAPK‑mediated COX‑2‑PGE2 pathway in MKN45 cells

N Liu, Q Wu, Y Wang, H Sui, X Liu… - Molecular …, 2014 - spandidos-publications.com
Helicobacter pylori has been suggested to be the major cause of gastric malignancy.
However, the pathogenesis and molecular mechanisms of gastric tumorigenesis induced by …

Over-expression of Ephb4 is associated with carcinogenesis of gastric cancer

M Li, ZW Zhao, Y Zhang, Y Xin - Digestive diseases and sciences, 2011 - Springer
Background Gastric cancer is one of the most frequently diagnosed malignancies in the
world. The gene expression profile and molecular grouping of gastric cancer has been a …

Cell-cycle regulators, bcl-2 and NF-κB in Epstein-Barr virus-positive gastric carcinomas

MS Chang, HS Lee, EJ Jung… - International …, 2005 - spandidos-publications.com
The mechanism by which Epstein-Barr virus (EBV) contributes to the carcinogenesis of
gastric mucosa remains unanswered. In this study, the role of cell-cycle regulators (p53, p21 …

Prognostic significance of p21WAF1/CIP1, p27Kip1, p53 and E-cadherin expression in gastric cancer

A Gamboa-Dominguez, S Seidl… - Journal of clinical …, 2007 - jcp.bmj.com
Background: Gastric carcinoma is characterised by numerous genetic and epigenetic
alterations that influence cell cycle progression, apoptosis and DNA repair. These …

High co-expression of Sp1 and HER-2 is correlated with poor prognosis of gastric cancer patients

W Jiang, Z Jin, F Zhou, J Cui, L Wang, L Wang - Surgical oncology, 2015 - Elsevier
The aim of this study was to investigate co-expression of HER-2 and Sp1 in gastric cancer
(GC) so as to determine whether these two proteins may be correlated with poor prognosis …