[HTML][HTML] Novel molecular targets in gastric adenocarcinoma

R Ramezankhani, R Solhi, HA Es, M Vosough… - Pharmacology & …, 2021 - Elsevier
Gastric adenocarcinoma (GAC) is the third leading cause of cancer-related death worldwide.
A high mortality rate and resistance to treatment protocols due to a heterogeneous …

[HTML][HTML] Comprehensive analysis reveals CTHRC1, SERPINE1, VCAN and UPK1B as the novel prognostic markers in gastric cancer

Z Zhu, J Xu, L Li, W Ye, B Chen, J Zeng… - Translational cancer …, 2020 - ncbi.nlm.nih.gov
Background Gastric cancer (GC) is one of the most common malignant diseases worldwide,
the incidence and mortality for GC is still high, thus it is urgently important to identify the …

A combination analysis of p53 and p21 in gastric carcinoma as a strong indicator for prognosis

M Ogawa, N Onoda, K Maeda… - International …, 2001 - spandidos-publications.com
We studied p53 and p21 expression simultaneously in gastric carcinoma tissues to
investigate the clinical significance of p53-p21 pathway in this disease. One hundred sixty …

[HTML][HTML] REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype

J Yu, Q Liang, J Wang, K Wang, J Gao, J Zhang… - Oncogene, 2017 - nature.com
REC8 meiotic recombination protein (REC8) was found to be preferentially methylated in
gastric cancer (GC) using promoter methylation array. We aimed to elucidate the epigenetic …

[HTML][HTML] ErbB1 and ErbB3 co-over expression as a prognostic factor in gastric cancer

M Moghbeli, Y Makhdoumi, MS Delgosha… - Biological …, 2019 - SciELO Chile
MOGHBELI, Meysam et al. ErbB1 and ErbB3 co-over expression as a prognostic factor in
gastric cancer. Biol. Res.[online]. 2019, vol. 52, 2. Epub 13-Jun-2019. ISSN 0716-9760 …

[HTML][HTML] P-Akt/miR‑200 signaling regulates epithelial-mesenchymal transition, migration and invasion in circulating gastric tumor cells

D Yuan, H Xia, Y Zhang, L Chen… - International …, 2014 - spandidos-publications.com
Both circulating tumor cells (CTCs) and epithelial-mesenchymal transition (EMT) play an
important role in invasion, migration and chemoresistant in tumor development. This study …

An immunohistochemical study of p16, pRb, p21 and p53 proteins in human esophageal cancers.

H Kato, M Yoshikawa, Y Fukai, K Tajima… - Anticancer …, 2000 - europepmc.org
Background Cell cycle-associated proteins, p16, pRb, p21 and p53 are important in
regulating the G1-S checkpoint in the cell cycle, and their functional alterations play key …

Role of EZH2 protein expression in gastric carcinogenesis among Asians: a meta-analysis

L Guo, TF Yang, SC Liang, JX Guo, Q Wang - Tumor Biology, 2014 - Springer
The present meta-analysis aggregated the results of relevant studies to identify the role of
zeste homolog 2 (EZH2) expression in gastric carcinogenesis among Asians. Related …

Different expression pattern and significance of p14ARF-Mdm2-p53 pathway and Bmi-1 exist between gastric cardia and distal gastric adenocarcinoma

D Yao, Y Wang, L Xue, H Wang, J Zhang, X Zhang - Human pathology, 2013 - Elsevier
Recent studies have suggested that adenocarcinoma of gastric cardia (GCA) is distinct from
distal stomach, with different risk factors, tumor characteristics, and biological behavior. The …

[HTML][HTML] Expression of p14ARF, p15INK4b, p16INK4a and skp2 increases during esophageal squamous cell cancer progression

P Bai, X Xiao, J Zou, L Cui… - Experimental and …, 2012 - spandidos-publications.com
Esophageal carcinoma is the sixth most common cause of cancer-related mortality in the
world. Senescence and apoptosis are assumed to be two main mechanisms that inhibit age …