Safety and efficacy of apixaban and rivaroxaban in obese patients with acute venous thrombosis/embolism.

N Anusim, B Ghimire, M Smalley… - European Journal …, 2022 - search.ebscohost.com
Of the 1731 patients in the rivaroxaban arm of this study, 245 patients had a weight > 100
kg but further classification into weight > 120 kg or BMI > 40 kg/m SP 2 sp was not …

[HTML][HTML] Direct oral anticoagulant dosing in extremes of body weight: time to revisit the guidelines?

AK Pandey, JW Eikelboom - Thrombosis and Haemostasis, 2021 - thieme-connect.com
Patients with high body weight are at increased risk of developing atrial fibrillation (AF) or
venous thromboembolism (VTE) and are often treated with antithrombotic drugs. 1 Direct …

Recurrent Venous Thromboembolism with Direct-Acting Oral Anticoagulants and Body Mass Index: A Single Institutional Study

SJ Gaddam, TS Brown, MK Salard, P Bhargava… - Blood, 2022 - ashpublications.org
Methods: After institutional review board approval, we conducted a retrospective chart
review for 1 year period (Jan 1, 2020-Dec 31, 2020) on all patients>/= 18 years of age who …

Use of direct oral anticoagulants for acute pulmonary embolisms in obesity: a propensity-matched, multicentre case–control study

CB Samaranayake, G Keir, SAA Slader… - ERJ Open …, 2021 - Eur Respiratory Soc
Direct oral anticoagulants (DOACs) are widely used as first-line treatment for pulmonary
embolism (PE) in patients without contraindications [1]; however, limited data exists on the …

Achieving Therapeutic Anti-Xa Levels Using Rivaroxaban for Venous Thromboembolism in a Morbidly Obese Patient with a BMI> 70

S Prakash, K Dah, S Ghafouri, A De La Rosa… - Blood, 2022 - ashpublications.org
Background: Anticoagulation (AC) is the cornerstone of treatment for venous
thromboembolism (VTE). Direct oral anticoagulants (DOACs) have become the standard of …

[HTML][HTML] Rivaroxaban versus warfarin treatment among morbidly obese patients with venous thromboembolism: comparative effectiveness, safety, and costs

AC Spyropoulos, V Ashton, YW Chen, B Wu… - Thrombosis research, 2019 - Elsevier
Introduction Limited data exist on direct-acting oral anticoagulants in morbidly obese
patients with venous thromboembolism (VTE). We compared clinical and health/economic …

[HTML][HTML] Outcome of morbidly obese patients with acute venous thromboembolism managed with direct oral anticoagulants

N Anusim, F Ionescu, V Jindal, R Gupta, I Jaiyesimi… - Blood, 2019 - Elsevier
Background. Obesity is a major epidemic affecting all age groups in the USA. It has been
associated with venous thromboembolism (VTE), which requires prolonged anticoagulation …

[PDF][PDF] Comparative efficacy and safety associated with apixaban and rivaroxaban treatment in morbidly obese versus non-obese patients

MF Duperreault, G Stern, J Rimsans… - Ann Cardiol Vasc …, 2020 - mail.meddocsonline.org
Background: Due to limited enrollment in landmark trials of patients with a BMI> 30 or
weight> 100 kg for apixaban and rivaroxaban, the International Society of Thrombosis and …

Apixaban and rivaroxaban in obese patients treated for venous thromboembolism: drug levels and clinical outcomes

A Ballerie, RN Van, K Lacut, H Galinat, C Rousseau… - Thrombosis research, 2021 - Elsevier
Background Direct oral anticoagulants (DOAC) use remains challenging in obese patients
treated for Venous-Thrombo-Embolism (VTE) due to the paucity of prospective and …

Direct oral anticoagulants and warfarin safety in rural patients with obesity

ZR Caverley, RJ Bindler, P Soh… - The American journal of the …, 2023 - Elsevier
Abstract Background Direct oral anticoagulants (DOACs) are often used in patients with
atrial fibrillation or flutter instead of warfarin and although supporting evidence is limited …