[HTML][HTML] Apixaban is safe and effective in morbidly obese patients: a retrospective analysis of 390 patients with BMI≥ 40
Y Choi, M Kushnir, HH Billett - Blood, 2017 - Elsevier
Background: In patients with venous thromboembolism (VTE), warfarin had been considered
standard of care until the new direct oral anticoagulants (DOACs) were developed. Studies …
standard of care until the new direct oral anticoagulants (DOACs) were developed. Studies …
Comparative effectiveness and safety of direct oral anticoagulants in obese patients with atrial fibrillation
Background Unlike warfarin direct oral anticoagulants (DOACs) are administered in fixed
doses, which raises concerns of its effectiveness on larger patients. Data from randomized …
doses, which raises concerns of its effectiveness on larger patients. Data from randomized …
Prescribing DOACs with specific patient populations in mind.
K Schleich, BE Ray - Journal of Family Practice, 2023 - search.ebscohost.com
The article focuses on the prescribing considerations of direct oral anticoagulants (DOACs)
for specific patient populations, including those with obesity, renal disease, cancer, and …
for specific patient populations, including those with obesity, renal disease, cancer, and …
[HTML][HTML] Peak plasma concentration of direct oral anticoagulants in obese patients weighing over 120 kilograms: a retrospective study
Background Due to a paucity of data on the efficacy and safety of direct oral anticoagulants
(DOACs) in patients with a body mass index> 40 kg/m 2 or a weight> 120 kg, the use of …
(DOACs) in patients with a body mass index> 40 kg/m 2 or a weight> 120 kg, the use of …
Comparative Effectiveness and Safety of Direct Oral Anticoagulants in Obese Patients with Atrial Fibrillation
B Alexandros, M Amgad, A Mazur… - … Drugs and Therapy, 2021 - search.proquest.com
Background Unlike warfarin direct oral anticoagulants (DOACs) are administered in fixed
doses, which raises concerns of its effectiveness on larger patients. Data from randomized …
doses, which raises concerns of its effectiveness on larger patients. Data from randomized …
Direct oral anticoagulants versus warfarin in morbidly obese patients with nonvalvular atrial fibrillation: a systematic review and meta-analysis
Background: Direct oral anticoagulants (DOACs) have been increasingly preferred over
warfarin; however, The International Society of Thrombosis and Hemostasis recommended …
warfarin; however, The International Society of Thrombosis and Hemostasis recommended …
Effectiveness and safety of apixaban vs. warfarin in venous thromboembolism patients with obesity and morbid obesity
This study integrated 5 United States healthcare claims databases to evaluate the risk of
recurrent venous thromboembolism (VTE) and major bleeding (MB) among VTE patients …
recurrent venous thromboembolism (VTE) and major bleeding (MB) among VTE patients …
Factor Xa inhibitors versus vitamin K antagonist in morbidly obese patients with venous thromboembolism: a systematic review and meta-analysis
Introduction Guidelines have endorsed non-vitamin K antagonist oral anticoagulants
(NOACs), consisting of factor Xa inhibitors (xabans) and direct thrombin inhibitors, as the first …
(NOACs), consisting of factor Xa inhibitors (xabans) and direct thrombin inhibitors, as the first …
Direct oral anticoagulant concentrations in obese and high body weight patients: a cohort study
AC Martin, W Thomas, Z Mahir… - Thrombosis and …, 2021 - thieme-connect.com
Background Direct oral anticoagulants (DOACs) are prescribed for atrial fibrillation (AF) and
venous thromboembolism (VTE) and both occur more frequently in obese patients …
venous thromboembolism (VTE) and both occur more frequently in obese patients …
Management of venous thromboembolism in morbidly obese patients: A 10-year review
B Wee, B Lui, J Lai, Z Khattak, A Kwok… - Journal of Thrombosis …, 2023 - Springer
Obesity is a known risk factor for venous thromboembolism (VTE) and poses a unique set of
challenges in anticoagulation management. We report a 10-year experience of VTE …
challenges in anticoagulation management. We report a 10-year experience of VTE …