Strategies for plasma proteomic profiling of cancers

GS Omenn - Proteomics, 2006 - Wiley Online Library
Despite a voluminous literature on potential protein biomarkers and a compelling need for
diagnostic tests based on biomarkers to detect cancers at much earlier, more treatable …

Proteomic approaches for cancer biomarker discovery in plasma

SJ Pitteri, SM Hanash - Expert review of proteomics, 2007 - Taylor & Francis
In recent years, many advances have been made in the field of proteomics. The use of high-
throughput methods for analyzing complex proteomes, in particular SELDI mass …

Cancer proteomics: serum diagnostics for tumor marker discovery

AJ Rai, DW Chan - Annals of the New York Academy of …, 2004 - Wiley Online Library
Cancer proteomics is an exciting field that is witnessing many new developments in recent
years. It is hoped that these advances will result in decreased cancer death rates, which …

Challenges and opportunities in clinical applications of blood-based proteomics in cancer

R Bhawal, AL Oberg, S Zhang, M Kohli - Cancers, 2020 - mdpi.com
Simple Summary The traditional approach in identifying cancer related protein biomarkers
has focused on evaluation of a single peptide/protein in tissue or circulation. At best, this …

Clinical cancer proteomics: promises and pitfalls

A Alaiya, M Al-Mohanna, S Linder - Journal of proteome research, 2005 - ACS Publications
Proteome analysis promises to be valuable for the identification of tissue and serum
biomarkers associated with human malignancies. In addition, proteome technologies offer …

The molecular make-up of a tumour: proteomics in cancer research

W Kolch, H Mischak, AR Pitt - Clinical Science, 2005 - portlandpress.com
The enormous progress in proteomics, enabled by recent advances in MS (mass
spectrometry), has brought protein analysis back into the limelight of cancer research …

Proteomic analysis in cancer research: potential application in clinical use

J García-Foncillas, E Bandrés, R Zárate… - Clinical & Translational …, 2006 - Springer
The ultimate goal of cancer proteomics is to adapt proteomic technologies for routine use in
clinical laboratories for the purpose of diagnostic and prognostic classification of disease …

Proteomic applications for the early detection of cancer

JD Wulfkuhle, LA Liotta, EF Petricoin - Nature reviews cancer, 2003 - nature.com
The ability of physicians to effectively treat and cure cancer is directly dependent on their
ability to detect cancers at their earliest stages. Proteomic analyses of early-stage cancers …

Proteomic approaches in cancer risk and response assessment

EF Petricoin, LA Liotta - Trends in molecular medicine, 2004 - cell.com
Proteomics is more than just a list-generating exercise where increases or decreases in
protein expression are identified. Proteomic technologies will ultimately characterize …

Application of proteomics to cancer early detection

S Hanash, A Taguchi - The Cancer Journal, 2011 - journals.lww.com
Strategies to achieve personalized medicine and improve public health encompass
assessment of an individual's risk for disease, early detection, and molecular classification of …