[HTML][HTML] Resveratrol Inhibits TNF-α–Induced Proliferation and Matrix Metalloproteinase Expression in Human Vascular Smooth Muscle Cells

B Lee, SK Moon - The Journal of nutrition, 2005 - Elsevier
Resveratrol (RV), a polyphenolic substance found in grape skin, was suggested to play a
role in preventing the development of atherosclerotic disease. Although RV has …

[HTML][HTML] Different short-and long-term effects of resveratrol on nuclear factor-κB phosphorylation and nuclear appearance in human endothelial cells

F Pellegatta, AAE Bertelli, B Staels, C Duhem… - The American journal of …, 2003 - Elsevier
Background: Resveratrol (a naturally occurring phytoalexin found in grapes and wine) has
cardiovascular protective effects that suggest the antiatherogenic (ie, antiinflammatory) …

Resveratrol inhibits rat aortic vascular smooth muscle cell proliferation via estrogen receptor dependent nitric oxide production

VP Ekshyyan, VY Hebert, A Khandelwal… - Journal of …, 2007 - journals.lww.com
Vascular smooth muscle cell (VSMC) proliferation is pivotal in the progression of
hypertension, atherosclerosis, and restenosis. Resveratrol is a grape polyphenol that is …

Resveratrol recruits rat muscle microvasculature via a nitric oxide-dependent mechanism that is blocked by TNFα

N Wang, SH Ko, W Chai, G Li… - American Journal …, 2011 - journals.physiology.org
Resveratrol, a polyphenol found in many plants, has antioxidant and anti-inflammatory
actions. It also improves endothelial function and may be cardioprotective. Tumor necrosis …

Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells

UGB Haider, D Sorescu, KK Griendling… - Molecular …, 2002 - ASPET
Resveratrol (RV), a polyphenolic substance found in grape skin, is proposed to account in
part for the protective effect of red wine in the cardiovascular system. Angiotensin II (Ang II) …

Resveratrol attenuates TNF-α-induced activation of coronary arterial endothelial cells: role of NF-κB inhibition

A Csiszar, K Smith, N Labinskyy… - American Journal …, 2006 - journals.physiology.org
Epidemiological studies suggest that Mediterranean diets rich in resveratrol are associated
with reduced risk of coronary artery disease. However, the mechanisms by which resveratrol …

Potential pro-inflammatory action of resveratrol in vascular smooth muscle cells from normal and diabetic rats

A Cignarella, C Minici, C Bolego, C Pinna… - Nutrition, metabolism …, 2006 - Elsevier
BACKGROUND AND AIM: Based on the reported cardioprotective effects of resveratrol, a
polyphenolic antioxidant abundant in grapes that binds to estrogen receptors, and the well …

Naringin inhibits matrix metalloproteinase‐9 expression and AKT phosphorylation in tumor necrosis factor‐α‐induced vascular smooth muscle cells

EJ Lee, DI Kim, WJ Kim… - Molecular nutrition & food …, 2009 - Wiley Online Library
Citrus fruits are high in naringin, which has a beneficial effect on cardiovascular diseases.
However, the matrix metalloproteinase‐9 (MMP‐9) regulation involved in cell migration and …

Profound negative regulatory effects by resveratrol on vascular smooth muscle cells: a role of p53–p21WAF1/CIP1 pathway

ZH Mnjoyan, K Fujise - Biochemical and Biophysical Research …, 2003 - Elsevier
We investigated the role of resveratrol, a polyphenol rich in red wine, in cell cycle
progression and apoptosis of vascular smooth muscle cells (VSMCs). Resveratrol inhibited …

Protective effects of chronic resveratrol treatment on vascular inflammatory injury in streptozotocin-induced type 2 diabetic rats: Role of NF-kappa B signaling

X Zheng, S Zhu, S Chang, Y Cao, J Dong, J Li… - European Journal of …, 2013 - Elsevier
Type 2 diabetes mellitus (T2DM) is associated with an increased risk of macrovascular
disease. Epidemiological studies suggest that plant polyphenol resveratrol (REV) is …