[HTML][HTML] Glypican-3 is a prognostic factor and an immunotherapeutic target in hepatocellular carcinoma
Y Haruyama, H Kataoka - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
Abstract Glypican-3 (GPC3) is a cell surface oncofetal proteoglycan that is anchored by
glycosylphosphatidylinositol. Whereas GPC3 is abundant in fetal liver, its expression is …
glycosylphosphatidylinositol. Whereas GPC3 is abundant in fetal liver, its expression is …
[HTML][HTML] Glypican-3: a molecular marker for the detection and treatment of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a malignant tumor with a fairly poor prognosis (5-year
survival of less than 50%). Using sorafenib, the only food and drug administration (FDA) …
survival of less than 50%). Using sorafenib, the only food and drug administration (FDA) …
Overexpression of glypican-3 is a predictor of poor prognosis in hepatocellular carcinoma: An updated meta-analysis
J Zhang, M Zhang, H Ma, X Song, L He, X Ye, X Li - Medicine, 2018 - journals.lww.com
Background: Glypican-3 (GPC3) has been widely recognized in the progression of liver
tumors for several years. The relationship between overexpression of GPC3 and the poorer …
tumors for several years. The relationship between overexpression of GPC3 and the poorer …
[HTML][HTML] Evaluating clinical and prognostic implications of Glypican-3 in hepatocellular carcinoma
AO Kaseb, M Hassan, S Lacin, R Abdel-Wahab… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most deadly cancers worldwide. In patients
with HCC, histopathogical differentiation is an important indicator of prognosis; however …
with HCC, histopathogical differentiation is an important indicator of prognosis; however …
Prognostic significance of glypican-3 in hepatocellular carcinoma: a meta-analysis
WK Xiao, CY Qi, D Chen, SQ Li, SJ Fu, BG Peng… - Bmc Cancer, 2014 - Springer
Abstract Backgrounds Glypican-3 (GPC3) has been implicated in tumor development and
progression for several years. However, the prognostic significance of GPC3 expression in …
progression for several years. However, the prognostic significance of GPC3 expression in …
Therapeutic potential of targeting glypican-3 in hepatocellular carcinoma
M Allegretta, J Filmus - Anti-Cancer Agents in Medicinal …, 2011 - ingentaconnect.com
Glypican-3 (GPC3) is a developmentally-regulated oncofetal protein that has been
established as a clinically-relevant biomarker for early hepatocellular carcinoma (HCC). It is …
established as a clinically-relevant biomarker for early hepatocellular carcinoma (HCC). It is …
Prognostic significance of circumferential cell surface immunoreactivity of glypican‐3 in hepatocellular carcinoma
K Yorita, N Takahashi, H Takai, A Kato… - Liver …, 2011 - Wiley Online Library
Background: GC33 is a recently developed monoclonal antibody against human glypican‐3
(GPC3), which is significantly upregulated in hepatocellular carcinoma (HCC). GC33 …
(GPC3), which is significantly upregulated in hepatocellular carcinoma (HCC). GC33 …
GPC-3 in hepatocellular carcinoma: current perspectives
Y Wu, H Liu, H Ding - Journal of hepatocellular carcinoma, 2016 - Taylor & Francis
Glypican-3 (GPC3), a member of heparan sulfate proteoglycans, attaches to the cell
membrane and is frequently observed to be elevated in hepatocellular carcinoma (HCC) …
membrane and is frequently observed to be elevated in hepatocellular carcinoma (HCC) …
Glypican 3-targeted therapy in hepatocellular carcinoma
T Nishida, H Kataoka - Cancers, 2019 - mdpi.com
Glypican-3 (GPC3) is an oncofetal glycoprotein attached to the cell membrane by a
glycophosphatidylinositol anchor. GPC3 is overexpressed in some kinds of tumors …
glycophosphatidylinositol anchor. GPC3 is overexpressed in some kinds of tumors …
Next-generation cancer immunotherapy targeting glypican-3
Y Shimizu, T Suzuki, T Yoshikawa, I Endo… - Frontiers in …, 2019 - frontiersin.org
Glypican-3 (GPC3), a 65 kD protein consisting of 580 amino acids, is a heparan sulfate
proteoglycan bound to the cell membrane by glycosylphosphatidylinositol. This protein is …
proteoglycan bound to the cell membrane by glycosylphosphatidylinositol. This protein is …
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