Rapid microbiology screening in pharmaceutical workflows

C Surrette, B Scherer, A Corwin… - SLAS …, 2018 - journals.sagepub.com
Recently advances in miniaturization and automation have been utilized to rapidly decrease
the time to result for microbiology testing in the clinic. These advances have been made due …

Verification of an automated, digital dispensing platform for at-will broth microdilution-based antimicrobial susceptibility testing

KP Smith, JE Kirby - Journal of clinical microbiology, 2016 - Am Soc Microbiol
With rapid emergence of multidrug-resistant bacteria, there is often a need to perform
susceptibility testing for less commonly used or newer antimicrobial agents. Such testing can …

Fully Integrated and High‐Throughput Microfluidic System for Multiplexed Point‐Of‐Care Testing

S Li, Y Zhang, J Liu, X Wang, C Qian, J Wang, L Wu… - Small, 2024 - Wiley Online Library
For every epidemic outbreak, the prevention and treatments in resource‐limited areas are
always out of reach. Critical to this is that high accuracy, stability, and more comprehensive …

A Fully integrated in vitro diagnostic microsystem for pathogen detection developed using a “3D Extensible” microfluidic design paradigm

Z Geng, Y Gu, S Li, B Lin, P Liu - Micromachines, 2019 - mdpi.com
Microfluidics is facing critical challenges in the quest of miniaturizing, integrating, and
automating in vitro diagnostics, including the increasing complexity of assays, the gap …

Rapid phenotypic antibiotic susceptibility testing of uropathogens using optical signal analysis on the nanowell slide

M Veses-Garcia, H Antypas, S Löffler… - Frontiers in …, 2018 - frontiersin.org
Achieving fast antimicrobial susceptibility results is a primary goal in the fight against
antimicrobial resistance. Standard antibiotic susceptibility testing (AST) takes, however, at …

Urchin-Shaped Au–Ag@ Pt Sensor Integrated Lateral Flow Immunoassay for multimodal detection and specific discrimination of clinical multiple bacterial infections

X Huang, L Chen, W Zhi, R Zeng, G Ji, H Cai… - Analytical …, 2023 - ACS Publications
A new lateral flow immunoassay strip (LFIA) combining sensitive detection and identification
of multiple bacteria remains a huge challenge. In this study, we first developed …

Combinatorial antimicrobial susceptibility testing enabled by non-contact printing

AS Opalski, A Ruszczak, Y Promovych, M Horka… - Micromachines, 2020 - mdpi.com
We demonstrate the utility of non-contact printing to fabricate the mAST—an easy-to-
operate, microwell-based microfluidic device for combinatorial antibiotic susceptibility testing …

Microfluidic designs and techniques using lab-on-a-chip devices for pathogen detection for point-of-care diagnostics

AM Foudeh, TF Didar, T Veres, M Tabrizian - Lab on a Chip, 2012 - pubs.rsc.org
Effective pathogen detection is an essential prerequisite for the prevention and treatment of
infectious diseases. Despite recent advances in biosensors, infectious diseases remain a …

Ratiometric PCR in a Portable Sample-to-Result Device for Broad-Based Pathogen Identification

FE Chen, AY Trick, AC Hasnain, K Hsieh… - Analytical …, 2022 - ACS Publications
Polymerase chain reaction (PCR)-based diagnostic testing is the gold standard method for
pathogen identification (ID) with recent developments enabling automated PCR tests for …

Application of microfluidics for bacterial identification

F Daniel, D Kesterson, K Lei, C Hord, A Patel… - Pharmaceuticals, 2022 - mdpi.com
Bacterial infections continue to pose serious public health challenges. Though anti-bacterial
therapeutics are effective remedies for treating these infections, the emergence of antibiotic …