Rapid phenotypic antimicrobial susceptibility testing using a coulter counter and proliferation rate discrepancy

Q Yi, J Cui, M Xiao, MZ Tang, HC Zhang, G Zhang… - Acs Omega, 2023 - ACS Publications
The rapid determination of antimicrobial susceptibility and evidence-based antimicrobial
prescription is necessary to combat widespread antimicrobial resistance and promote …

Simplifying the complex: accessible microfluidic solutions for contemporary processes within in vitro diagnostics

NK Khosla, JM Lesinski, M Colombo, L Bezinge… - Lab on a Chip, 2022 - pubs.rsc.org
In vitro diagnostics (IVDs) form the cornerstone of modern medicine. They are routinely
employed throughout the entire treatment pathway, from initial diagnosis through to …

Live biosensors for ultrahigh-throughput screening of antimicrobial activity against Gram-negative bacteria

MN Baranova, PA Babikova, AM Kudzhaev… - Antibiotics, 2021 - mdpi.com
Gram-negative pathogens represent an urgent threat due to their intrinsic and acquired
antibiotic resistance. Many recent drug candidates display prominent antimicrobial activity …

Polydisperse emulsion digital assay to enhance time to detection and extend dynamic range in bacterial cultures enabled by a statistical framework

SA Byrnes, EA Phillips, T Huynh, BH Weigl, KP Nichols - Analyst, 2018 - pubs.rsc.org
Microbiological culture remains the most sensitive method for detecting viable and infectious
bacteria, but these methods often require at least 24 hours to visibly identify bacterial growth …

Rapid and Accurate Antimicrobial Susceptibility Testing Using Label‐Free Electrical Impedance‐Based Microfluidic Platform

J Chen, J Zhong, Y Chang, Y Zhou, SH Koo, TY Tan… - Small, 2024 - Wiley Online Library
Antimicrobial resistance has become a serious threat to the global public health. Accurate
and rapid antimicrobial susceptibility testing (AST) allows evidence‐based prescribing of …

A digital–analog microfluidic platform for patient-centric multiplexed biomarker diagnostics of ultralow volume samples

F Piraino, F Volpetti, C Watson, SJ Maerkl - ACS nano, 2016 - ACS Publications
Microfluidic diagnostic devices have the potential to transform the practice of medicine. We
engineered a multiplexed digital–analog microfluidic platform for the rapid and highly …

Advancing point-of-care microbial pathogens detection by material-functionalized microfluidic systems

X Liao, Y Zhang, Q Zhang, J Zhou, T Ding… - Trends in Food Science & …, 2023 - Elsevier
Background Public health events caused by foodborne pathogens have brought substantial
economic and social burdens. Conventional pathogen detection relies on a time-consuming …

Microfluidics-based strategies for molecular diagnostics of infectious diseases

X Wang, XZ Hong, YW Li, Y Li, J Wang, P Chen… - Military Medical …, 2022 - Springer
Traditional diagnostic strategies for infectious disease detection require benchtop
instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a …

Rapid Antibiotic Susceptibility Testing of Uropathogenic E. coli by Tracking Submicron Scale Motion of Single Bacterial Cells

K Syal, S Shen, Y Yang, S Wang, SE Haydel… - ACS sensors, 2017 - ACS Publications
To combat antibiotic resistance, a rapid antibiotic susceptibility testing (AST) technology that
can identify resistant infections at disease onset is required. Current clinical AST …

[HTML][HTML] Pathogen detection on microfluidic platforms: Recent advances, challenges, and prospects

A Jagannath, H Cong, J Hassan, G Gonzalez… - … and Bioelectronics: X, 2022 - Elsevier
Abstract Point-Of-Care (POC) testing has advanced to more affordable and rapid
alternatives by adapting conventional immunoassays and molecular assays (isothermal …