The major burden of illness in bipolar disorder (BD) is in the depressive pole. Lamotrigine
has been shown to be useful in the long-term prophylaxis of depressive episodes in BD …

Objective: To investigate the safety of rechallenge with lamotrigine after an initial rash in
patients with refractory bipolar depression. Design: 1) Prospective, open-label case series in …

Background: The rate of lamotrigineassociated rash in patients with mood disorders has not
been well characterized. The objective of this report was to determine rash rates in clinical …

The goal of this study was to assess the incidence of rash occurring in patients received
lamotrigine to treat bipolar I disorder in a real world setting in Korea. We included a …

Lamotrigine (LTG) is associated with the potential for a life-threatening rash (eg, Stevens-
Johnson syndrome or toxic epidermal necrolysis). The incidence has been linked to rapid …

Objective: Prescribing recommendations specify that lamotrigine should ordinarily be
discontinued at the first sign of rash, regardless of its type and severity, unless the rash is …

Objective: To assess treatment-emergent rash incidence when using dermatology
precautions (limited antigen exposure) and slower titration during lamotrigine initiation …

Background: Although lamotrigine may be useful for treating patients with treatment-resistant
bipolar disorder, some lamotrigine-associated adverse effects, including mild to moderate …

Objectives–The only serious adverse event associated with lamotrigine (LTG) treatment is a
hypersensitivity reaction primarily presenting as a rash. Despite this concern, LTG is an …

Lamotrigine (LTG) is widely used for epilepsy and bipolar disorder.[1] However, there are
risks of LTG-induced skin rash. A total of 17 patients (5.5%) had an initial dose that was …